Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 13/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2464399 | 0.78 | MET (0.52) | METMEN1KMT2ATP53 | |
| SCHEMBL2467245 | 0.77 | MET (0.53) | METMEN1KMT2ATP53 | |
| SCHEMBL3087179 | 0.72 | MET (0.74) | METMEN1KMT2A | |
| SCHEMBL1151179 | 0.71 | MET (0.54) | METMEN1KMT2ATP53 | |
| SCHEMBL2466743 | 0.70 | MET (0.65) | METMEN1KMT2A | |
| SCHEMBL13089765 | 0.70 | MEN1 (0.70) | METMEN1KMT2A | |
| SCHEMBL1952616 | 0.70 | MET (0.65) | METMEN1KMT2A | |
| SCHEMBL1303077 | 0.70 | MET (0.65) | METMEN1KMT2A | |
| SCHEMBL13561689 | 0.70 | MET (0.74) | METMEN1KMT2A | |
| SCHEMBL17850432 | 0.69 | MET (0.54) | METMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960370-B1 | PYRIDIAZINONE DERIVATIVES FOR TUMOUR TREATMENT | MERCK PATENT GMBH (DE) | 2011-10-05 | — | — | EP | claimed |
| EP-1960370-B1 | PYRIDIAZINONE DERIVATIVES FOR TUMOUR TREATMENT | MERCK PATENT GMBH (DE) | 2011-10-05 | — | — | EP | disclosed |