SCHEMBL2468892

SCHEMBL2468892

O=C(O)c1[c]ccc(S(=O)(=O)O)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
HSD17B10 Q99714 4/20 0.44
KDM4E B2RXH2 1/20 0.44
HPGD P15428 1/20 0.44
LCK P06239 1/20 0.44
FYN P06241 1/20 0.44
TSHR P16473 3/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TDP1 Q9NUW8 1/20 0.37
LMNA P02545 1/20 0.34
SNCA P37840 1/20 0.34
S1PR3 Q99500 1/20 0.34
NT5E P21589 1/20 0.33
CASR P41180 3/20 0.33
PHLPP2 Q6ZVD8 1/20 0.33
TIMP3 P35625 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4321490 0.74 KEAP1 (0.39) ALDH1A1HSD17B10KDM4EHPGDTSHR
SCHEMBL1373270 0.74 ALDH1A1 (0.41) ALDH1A1HSD17B10KDM4EHPGDLCK
SCHEMBL6241506 0.74 ALDH1A1 (0.44) ALDH1A1HSD17B10KDM4EHPGDLCK
SCHEMBL3810665 0.72 ALDH1A1 (0.39) ALDH1A1HSD17B10KDM4EHPGDLCK
SCHEMBL7048593 0.72 ALDH1A1 (0.39) ALDH1A1HSD17B10KDM4EHPGDLCK
SCHEMBL5505800 0.72 ALDH1A1 (0.39) ALDH1A1HSD17B10KDM4EHPGDLCK
SCHEMBL2778706 0.72 ALDH1A1 (0.48) ALDH1A1HSD17B10KDM4EHPGDLCK
SCHEMBL4358128 0.72 ALDH1A1 (0.39) ALDH1A1HSD17B10KDM4EHPGDLCK
SCHEMBL5857066 0.71 KDM4E (0.42) ALDH1A1HSD17B10KDM4EHPGDTSHR
SCHEMBL490251 0.71 KDM4E (0.42) ALDH1A1HSD17B10KDM4EHPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1975205-B1 TRISAZO COMPOUND, INK COMPOSITION, RECORDING METHOD AND COLORED MATTER NIPPON KAYAKU KK (JP) 2012-05-02 EP claimed
US-8167991-B2 Trisazo compound, ink composition, recording method, and colored article NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-05-01 US claimed
EP-1506261-B1 TRISAZO DYES FOR INK JET PRINTING FUJIFILM IMAGING COLORANTS LTD (GB) 2009-11-18 EP claimed
US-20090062545-A1 Trisazo Compound, Ink Composition, Recording Method, and Colored Article NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2009-03-05 US claimed
EP-1975205-A1 TRISAZO COMPOUND, INK COMPOSITION, RECORDING METHOD AND COLORED MATTER Nipponkayaku Kabushikikaisha (JP) 2008-10-01 EP claimed
US-7052538-B2 Trisazo dyes for ink jet printing AVECIA LIMITED (GB) 2006-05-30 US claimed
US-20050217535-A1 Trisazo dyes for ink jet printing AVECIA INKJET LIMITED (GB) 2005-10-06 US claimed
EP-1506261-A1 TRISAZO DYES FOR INK JET PRINTING Avecia Limited (GB) 2005-02-16 EP claimed
WO-2003095562-A1 TRISAZO DYES FOR INK JET PRINTING AVECIA LIMITED (GB) 2003-11-20 WO claimed
EP-0458442-B1 Colorants BASF AG (DE) 1997-08-20 EP claimed
EP-0527186-A4 UNIV ILLINOIS (US) 1995-01-18 EP claimed
EP-0527186-A1 PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS The Board of Trustees for the University of Illinois (US) 1993-02-17 EP claimed
EP-0278910-B1 HEAVY METAL COMPLEX DYESTUFFS, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1992-01-22 EP claimed
WO-1991016820-A1 PHOTODYNAMIC PLANT DEFOLIANTS AND CHLOROPHYLL BIOSYNTHESIS MODULATORS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1991-11-14 WO claimed
EP-0050266-B1 REACTIVE DISAZO DYES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING AND PRINTING MATERIALS THAT CONTAIN HYDROXYL AND/OR NITROGEN BAYER AG (DE) 1984-10-03 EP claimed
US-20220162419-A1 COLORED CURABLE RESIN COMPOSITION, COLOR FILTER AND SOLID-STATE IMAGING ELEMENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-05-26 US disclosed
EP-3950726-A1 COLORED CURABLE RESIN COMPOSITION, COLOR FILTER AND SOLID-STATE IMAGING ELEMENT Sumitomo Chemical Company, Limited (JP) 2022-02-09 EP disclosed
EP-0101408-B1 MONOAZO DYESTUFFS, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1986-05-07 EP disclosed
EP-0050266-B1 REACTIVE DISAZO DYES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING AND PRINTING MATERIALS THAT CONTAIN HYDROXYL AND/OR NITROGEN BAYER AG (DE) 1984-10-03 EP disclosed
EP-0111830-A2 Water soluble monoazo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1984-06-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090062545-A1 Trisazo Compound, Ink Composition, Recording Method, and Colored Article JAK1, TMT1A, CDK1 ALDH1A1 2569/4885HSD17B10 4469/4885KDM4E 1223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.