Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9917422 | 0.83 | HDAC6 (0.54) | MAPTHDAC6RAB9ADUSP3SMN1; SMN2 | |
| SCHEMBL375814 | 0.82 | HDAC6 (0.51) | MAPTHDAC6L3MBTL1SOS1 | |
| SCHEMBL13042 | 0.81 | NPC1 (0.50) | MAPTRAB9ASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL693201 | 0.80 | DRD2 (0.46) | MAPTKDM4EALDH1A1EPHB4TEK | |
| SCHEMBL6844901 | 0.80 | PTGER4 (0.46) | P2RY14HDAC6HDAC1 | |
| SCHEMBL24690109 | 0.79 | NOS1 (0.43) | MAPT | |
| SCHEMBL17136785 | 0.78 | MAPT (0.37) | MAPTHDAC6EPHB4TEK | |
| SCHEMBL16772292 | 0.76 | SMN1; SMN2 (0.45) | HDAC6RAB9ADUSP3SMN1; SMN2L3MBTL1 | |
| SCHEMBL18470552 | 0.76 | ESR2 (0.43) | MAPTRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL693468 | 0.76 | DRD2 (0.38) | MAPTHDAC6SOS1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022224212-A1 | GPR35 AGONIST COMPOUNDS | HEPTARES THERAPEUTICS LIMITED (GB) | 2022-10-27 | — | — | WO | disclosed |