Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 6/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | LIPE | Q05469 | 1/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3040045 | 0.82 | SLC2A1 (0.57) | MRGPRX4MAOBIDO1THRBPTPN1 | |
| SCHEMBL510047 | 0.82 | MAOB (0.49) | MAOBIDO1KMT2AKDM4E | |
| SCHEMBL21327422 | 0.82 | GRM5 (0.40) | MRGPRX4MAOBTHRBADAMTS4KDM4E | |
| SCHEMBL5652023 | 0.81 | MAOB (0.62) | MRGPRX4MAOBIDO1LIPEKMT2A | |
| SCHEMBL30354929 | 0.81 | MAOB (0.62) | MRGPRX4MAOBIDO1LIPEKMT2A | |
| SCHEMBL24400853 | 0.81 | MAOB (0.60) | MRGPRX4MAOBIDO1LIPEADAMTS4 | |
| SCHEMBL24690108 | 0.81 | MRGPRX4 (0.47) | MRGPRX4MAOBIDO1LIPEADAMTS4 | |
| SCHEMBL24400852 | 0.79 | ALDH1A1 (0.54) | MRGPRX4MAOBIDO1PTPN1LIPE | |
| SCHEMBL18429708 | 0.79 | APP (0.59) | IDO1KDM4E | |
| SCHEMBL510168 | 0.78 | GABRA5 (0.52) | MAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4326708-A1 | GPR35 AGONIST COMPOUNDS | Heptares Therapeutics Limited (GB) | 2024-02-28 | — | — | EP | disclosed |
| CN-117529472-A | GPR35 agonist compounds | 赫普泰雅治疗有限公司 | 2024-02-06 | — | — | CN | disclosed |
| WO-2022224212-A1 | GPR35 AGONIST COMPOUNDS | HEPTARES THERAPEUTICS LIMITED (GB) | 2022-10-27 | — | — | WO | disclosed |
| WO-2022224212-A1 | GPR35 AGONIST COMPOUNDS | HEPTARES THERAPEUTICS LIMITED (GB) | 2022-10-27 | — | — | WO | disclosed |