Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 7/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | LIPE | Q05469 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5652023 | 0.81 | MAOB (0.62) | MRGPRX4MAOBIDO1LIPEKMT2A | |
| SCHEMBL24400853 | 0.81 | MAOB (0.60) | MRGPRX4MAOBIDO1LIPEADAMTS4 | |
| SCHEMBL30354929 | 0.81 | MAOB (0.62) | MRGPRX4MAOBIDO1LIPEKMT2A | |
| SCHEMBL24690180 | 0.81 | MRGPRX4 (0.47) | MRGPRX4MAOBIDO1LIPEADAMTS4 | |
| SCHEMBL24690163 | 0.80 | NOS1 (0.43) | MAOBLIPEGABRA5HPGDMAPT | |
| SCHEMBL16838859 | 0.79 | LIPE (0.55) | MRGPRX4MAOBLIPEGABRA5ADAMTS4 | |
| SCHEMBL24400852 | 0.79 | ALDH1A1 (0.54) | MRGPRX4MAOBIDO1LIPEADAMTS4 | |
| SCHEMBL18256806 | 0.79 | LMNA (0.42) | MAOBIDO1GABRA5RXRAGRIN1 | |
| SCHEMBL510525 | 0.79 | MAOB (0.45) | MAOBIDO1GABRA5RXRAKMT2A | |
| SCHEMBL2243975 | 0.79 | MAOB (0.45) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022224212-A1 | GPR35 AGONIST COMPOUNDS | HEPTARES THERAPEUTICS LIMITED (GB) | 2022-10-27 | — | — | WO | disclosed |