SCHEMBL24690929

SCHEMBL24690929

Cc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)CCl)cc12

nearest known ligand 0.71

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CTSB P07858 4/20 0.71
▸ CTSL P07711 3/20 0.71
▸ CTSS P25774 3/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24691113 0.93 CTSB (0.82) CTSBCTSLCTSS
SCHEMBL30002049 0.92 CTSL (0.70) CTSBCTSLCTSS
SCHEMBL24690572 0.92 CTSL (0.70) CTSBCTSLCTSS
SCHEMBL24691287 0.91 CTSL (0.68) CTSBCTSLCTSS
SCHEMBL30001311 0.91 CTSL (0.68) CTSBCTSLCTSS
SCHEMBL23782029 0.90 CTSB (0.87) CTSBCTSLCTSS
SCHEMBL34468113 0.90 CTSB (0.87) CTSBCTSLCTSS
SCHEMBL23782032 0.90 CTSB (0.87) CTSBCTSLCTSS
SCHEMBL23824683 0.90 CTSB (0.87) CTSBCTSLCTSS
SCHEMBL29393966 0.90 CTSB (0.87) CTSBCTSLCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250122153-A1 Protease Inhibitors as Antivirals ACEA Therapeutics, Inc. (US) 2025-04-17 — — US disclosed
US-11987554-B2 Protease inhibitors as antivirals VIVASOR, INC. (US) 2024-05-21 — — US disclosed
US-20230322668-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACEA Therapeutics, Inc. (US) 2023-10-12 — — US disclosed
US-20230322668-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACEA Therapeutics, Inc. (US) 2023-10-12 — — US disclosed
US-11753373-B2 Protease inhibitors as antivirals ACEA Therapeutics, Inc. (US) 2023-09-12 — — US disclosed
US-11753373-B2 Protease inhibitors as antivirals ACEA Therapeutics, Inc. (US) 2023-09-12 — — US disclosed
US-20230026438-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACEA Therapeutics, Inc. 2023-01-26 — — US disclosed
US-20230026438-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACEA Therapeutics, Inc. 2023-01-26 — — US disclosed
WO-2022256434-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACEA Therapeutics, Inc. (US) 2022-12-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122153-A1 Protease Inhibitors as Antivirals ACE, ACE2, TMPRSS15 CTSB 44/4885CTSL 4/4885CTSS 45/4885
US-20230026438-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACE, ACE2, TMPRSS15 CTSB 44/4885CTSL 4/4885CTSS 45/4885
US-11753373-B2 Protease inhibitors as antivirals ACE, ACE2, TMPRSS15 CTSB 44/4885CTSL 4/4885CTSS 45/4885
US-11987554-B2 Protease inhibitors as antivirals ACE, ACE2, TMPRSS15 CTSB 44/4885CTSL 4/4885CTSS 45/4885
US-20230322668-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACE, ACE2, TMPRSS15 CTSB 44/4885CTSL 4/4885CTSS 45/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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