Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.40 |
| ▸ | MPO | P05164 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 4/20 | 0.36 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | HTR1B | P28222 | 2/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29206444 | 1.00 | HTR2A (0.40) | HTR2AMPOHTR1AHTR1DHTR1B | |
| SCHEMBL29206362 | 0.84 | HTR2A (0.36) | HTR2AMPOHTR1AHTR1DHTR1B | |
| SCHEMBL29206367 | 0.82 | HTR2A (0.57) | HTR2AMPOHTR1AHTR1DHTR1B | |
| SCHEMBL29206392 | 0.81 | MTNR1A (0.43) | HTR2AHTR1AHTR1DHTR1BHTR6 | |
| SCHEMBL30877278 | 0.81 | MTNR1A (0.43) | HTR2AHTR1AHTR1DHTR1BHTR6 | |
| SCHEMBL29206408 | 0.80 | HTR2A (0.38) | HTR2AMPOHTR1AHTR1DHTR1B | |
| SCHEMBL25883633 | 0.77 | HTR2A (0.42) | HTR2AMPOHTR1AHTR1DHTR1B | |
| SCHEMBL24420288 | 0.77 | GPR84 (0.42) | HTR2AMPOHTR1AHTR1DHTR1B | |
| SCHEMBL29206370 | 0.76 | HTR2A (0.57) | HTR2AMPOHTR1AHTR1DHTR1B | |
| SCHEMBL24693005 | 0.75 | MPO (0.42) | MPOHTR1AHTR1DHTR1BGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022256554-A1 | FLUORINATED TRYPTAMINE COMPOUNDS, ANALOGUES THEREOF, AND METHODS USING SAME | UNIVERSITY OF THE SCIENCES (US) | 2022-12-08 | — | — | WO | disclosed |