Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL9246627 | 0.97 | ALDH1A1 (0.30) | ALDH1A1CASP1CASP7HSD17B10TDP1 | |
| SCHEMBL13836247 | 0.97 | ALDH1A1 (0.30) | ALDH1A1CASP1CASP7HSD17B10TDP1 | |
| SCHEMBL13835464 | 0.97 | ALDH1A1 (0.30) | ALDH1A1CASP1CASP7HSD17B10TDP1 | |
| SCHEMBL5697529 | 0.87 | ALDH1A1 (0.35) | ALDH1A1CASP1CASP7HSD17B10TDP1 | |
| SCHEMBL9403857 | 0.84 | CA1 (0.33) | ALDH1A1CASP1CASP7HSD17B10TDP1 | |
| Tetrabuthylammonium SCHEMBL11743739 | 0.83 | S1PR3 (0.33) | — | |
| SCHEMBL3337730 | 0.83 | CA1 (0.32) | ALDH1A1CASP1CASP7HSD17B10TDP1 | |
| Potassium Ion SCHEMBL2231008 | 0.83 | NFKB1 (0.31) | — | |
| SCHEMBL672196 | 0.83 | NFKB1 (0.33) | TDP1LMNA | |
| Potassium Ion SCHEMBL8338015 | 0.77 | CA1 (0.38) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006028647-A1 | PROCESS FOR PRODUCING A WOLLASTONITE CONTAINING POLYESTER AND PRODUCTS AND ARTICLES PRODUCED THEREFROM | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-03-16 | — | — | WO | claimed |
| US-20060036012-A1 | Process for producing a wollastonite containing polyester and products and articles produced therefrom | E. I. DU PONT DE NEMOURS AND COMPANY | 2006-02-16 | — | — | US | claimed |
| EP-1368404-A1 | SULFOISOPHTHALIC ACID SOLUTION AND PROCESS THEREWITH | E. I. du Pont de Nemours and Company (US) | 2003-12-10 | — | — | EP | claimed |
| US-20020169273-A1 | Sulfoisophthalic acid solution and process therewith | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-11-14 | — | — | US | claimed |
| US-6479619-B1 | PRODUCING A PARTIALLY ESTERIFIED ALKALI METAL SULFOISOPHTHALIC ACID IN A GLYCOL; CAN BE MADE IMMEDIATELY PRIOR TO USE; COPOLYMERIZING WITH TEREPHTHALIC ACID AND A GLYCOL TO FORM A POLYESTER | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-11-12 | — | — | US | claimed |
| WO-2002074834-A1 | SULFOISOPHTHALIC ACID SOLUTION AND PROCESS THEREWITH | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-09-26 | — | — | WO | claimed |
| EP-1664152-B1 | IONOMERIC OXYGEN SCAVENGER COMPOSITIONS | CRYOVAC INC (US) | 2011-10-05 | — | — | EP | disclosed |
| EP-1773924-A1 | ELECTRICALLY CONDUCTIVE POLYETHERESTER COMPOSITION COMPRISING CARBON BLACK AND PRODUCT MADE THEREFROM | E.I.Du pont de nemours and company (US) | 2007-04-18 | — | — | EP | disclosed |
| US-20070007495-A1 | Electrically conductive polyetherester composition comprising carbon black and product made therefrom | E. I. DU PONT DE NEMOURS AND COMPANY | 2007-01-11 | — | — | US | disclosed |
| WO-2006069132-A1 | POLYESTERS CONTAINING NATURAL MINERAL MATERIALS, PROCESSES FOR PRODUCING SUCH POLYESTERS, AND SHAPED ARTICLES PRODUCED THEREFROM | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-06-29 | — | — | WO | disclosed |
| US-20060135668-A1 | Polyesters containing natural mineral materials, processes for producing such polyesters, and shaped articles produced therefrom | E. I. DU PONT DE NEMOURS AND COMPANY | 2006-06-22 | — | — | US | disclosed |
| US-20060036012-A1 | Process for producing a wollastonite containing polyester and products and articles produced therefrom | E. I. DU PONT DE NEMOURS AND COMPANY | 2006-02-16 | — | — | US | disclosed |
| WO-2006009762-A1 | ELECTRICALLY CONDUCTIVE POLYETHERESTER COMPOSITION COMPRISING CARBON BLACK AND PRODUCT MADE THEREFROM | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-01-26 | — | — | WO | disclosed |
| WO-2005068530-A1 | POLYESTER COMPOSITION COMPRISING CARBON BLACK | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2005-07-28 | — | — | WO | disclosed |
| US-20050154118-A1 | Homo or copolymerizing a dicarboxylic acid, a glycol in presence of low level of carbon black to produce a polyester having electric properties and lower product melt viscosity | E. I. DU PONT DE NEMOURS AND COMPANY | 2005-07-14 | — | — | US | disclosed |
| US-5407981-A | Reacting ester of dibasic acid, short chain diol,long chain polyglycol, alkali salt of dialkylsulfoisophthalate, stabilizers and alkali salt of phenol; for extrusion, blow molding | CHEIL SYNTHETICS INC. (KR) | 1995-04-18 | — | — | US | disclosed |
| EP-0605260-A1 | Preparation of polyether ester elastomers having high melt viscosities and crystallization | CHEIL SYNTHETICS INC. (KR) | 1994-07-06 | — | — | EP | disclosed |