SCHEMBL2469328

SCHEMBL2469328

C=C(C(=O)COC(C)=O)C(=O)OCCC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
ALDH1A1 P00352 6/20 0.41
THRB P10828 1/20 0.39
LMNA P02545 2/20 0.37
HSD17B10 Q99714 1/20 0.37
FAAH O00519 1/20 0.35
CHRM5 P08912 2/20 0.34
CHRM1 P11229 2/20 0.34
CHRM3 P20309 2/20 0.34
HCAR2 Q8TDS4 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
GAA P10253 2/20 0.32
GALR3 O60755 2/20 0.32
PGR P06401 1/20 0.31
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
HTR1A P08908 1/20 0.31
CHRNB2 P17787 1/20 0.31
TBXA2R P21731 1/20 0.31
CHRNB4 P30926 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2466880 0.85 ALDH1A1 (0.50) TSHRALDH1A1THRBLMNAHSD17B10
SCHEMBL6659743 0.81 TSHR (0.44) TSHRALDH1A1THRBLMNAHSD17B10
SCHEMBL5871999 0.80 TSHR (0.48) TSHRALDH1A1THRBLMNACHRM1
SCHEMBL27333392 0.79 TSHR (0.43) TSHRALDH1A1THRBLMNACHRM1
SCHEMBL5408195 0.78 TSHR (0.48) TSHRALDH1A1THRBLMNAHSD17B10
SCHEMBL2470732 0.75 TSHR (0.40) TSHRALDH1A1THRBLMNAHSD17B10
SCHEMBL15536700 0.74 ALDH1A1 (0.47) TSHRALDH1A1THRBLMNAHSD17B10
SCHEMBL629109 0.74 TSHR (0.44) TSHRALDH1A1THRBLMNACHRM1
SCHEMBL21772349 0.73 TSHR (0.69) TSHRALDH1A1THRBLMNAHSD17B10
SCHEMBL16573 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102153314-B The consolidated structures body being applicable to the two-pack mortar material of structure object, its purposes and being obtained by it HILTI AG (LI) 2015-11-25 CN disclosed
US-8716368-B2 Unsaturated polyester resin or vinyl ester resin composition DSM IP ASSETS B.V. (NL) 2014-05-06 US disclosed
EP-1888680-B1 UNSATURATED POLYESTER RESIN OR VINYL ESTER RESIN COMPOSITION DSM IP ASSETS BV (NL) 2011-10-05 EP disclosed
US-20090156750-A1 Unsaturated polyester resin or vinyl ester resin composition DSM IP ASSETS B.V. (NL) 2009-06-18 US disclosed
EP-1888680-A1 UNSATURATED POLYESTER RESIN OR VINYL ESTER RESIN COMPOSITION DSMIP Assets B.V. (NL) 2008-02-20 EP disclosed
WO-2006131295-A1 UNSATURATED POLYESTER RESIN OR VINYL ESTER RESIN COMPOSITION DSM IP ASSETS B.V. (NL) 2006-12-14 WO disclosed