SCHEMBL629109

SCHEMBL629109

C=C(C(=O)O)C(=O)OCCC

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.44
HCAR2 Q8TDS4 1/20 0.42
THRB P10828 1/20 0.41
GAA P10253 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
LMNA P02545 2/20 0.39
ALDH1A1 P00352 6/20 0.39
MAPT P10636 1/20 0.39
ESR1 P03372 1/20 0.34
CHRM1 P11229 1/20 0.34
SLC6A2 P23975 1/20 0.34
KDR P35968 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
HPGD P15428 1/20 0.33
PPM1B O75688 1/20 0.33
PTPN1 P18031 1/20 0.33
PPP1CC P36873 1/20 0.33
RAD52 P43351 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5871999 0.88 TSHR (0.48) TSHRHCAR2THRBGAASMN1; SMN2
SCHEMBL6655862 0.87 TSHR (0.55) TSHRHCAR2THRBSMN1; SMN2LMNA
SCHEMBL1978864 0.85 THRB (0.41) TSHRTHRBALDH1A1MAPTTDP1
SCHEMBL2522294 0.85 TSHR (0.63) TSHRHCAR2LMNAALDH1A1HPGD
SCHEMBL6663986 0.84 TSHR (0.67) TSHRHCAR2LMNAALDH1A1RAD52
SCHEMBL6656362 0.84 TSHR (0.67) TSHRHCAR2LMNAALDH1A1RAD52
SCHEMBL6663377 0.84 TSHR (0.67) TSHRHCAR2LMNAALDH1A1RAD52
SCHEMBL31622785 0.84 TSHR (0.67) TSHRHCAR2LMNAALDH1A1RAD52
SCHEMBL5050880 0.84 TSHR (0.67) TSHRHCAR2LMNAALDH1A1RAD52
SCHEMBL15536700 0.82 ALDH1A1 (0.47) TSHRHCAR2THRBGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020123579-A1 POLYMERIZATION OF 1,1-DICARBONYL 1-ALKENES SIRRUS, INC. (US) 2020-06-18 WO disclosed
WO-2020123581-A1 EMULSION POLYMERS OF 1,1-DICARBONYL 1-ALKENES OF CONTROLLED PARTICLE SIZE SIRRUS, INC. (US) 2020-06-18 WO disclosed
CN-104334659-B The excellent coating composition of tactile qualities, its preparation method and the transfer sheet using this coating composition 乐金华奥斯有限公司 2017-03-01 CN disclosed
CN-104334659-A Coating composition with excellent tactile characteristics, preparation method thereof, and transfer sheet using same LG HAUSYS LTD 2015-02-04 CN disclosed
EP-2357214-B1 Coating and method for particle reduction 3M INNOVATIVE PROPERTIES CO (US) 2013-01-23 EP disclosed
EP-2231798-B1 Coatings for particle reduction 3M INNOVATIVE PROPERTIES CO (US) 2012-02-22 EP disclosed
EP-2357214-A1 Coating and method for particle reduction 3M Innovative Properties Company (US) 2011-08-17 EP disclosed
US-7923133-B2 Coatings and methods for particle reduction 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-04-12 US disclosed
EP-2231798-A1 COATINGS AND METHODS FOR PARTICLE REDUCTION 3M Innovative Properties Company (US) 2010-09-29 EP disclosed
WO-2009082599-A1 COATINGS AND METHODS FOR PARTICLE REDUCTION 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-07-02 WO disclosed
US-20090162700-A1 COATINGS AND METHODS FOR PARTICLE REDUCTION 3M INNOVATIVE PROPERTIES COMPANY 2009-06-25 US disclosed
EP-1123915-B1 Process for producing alpha, beta-unsaturated carboxylic acid esters and catalyst for use in such process NIPPON CATALYTIC CHEM IND (JP) 2004-07-28 EP disclosed
US-6541656-B2 Reacting an alpha, beta unsaturated carboxylic acid ester with a heterocyclic oxygen nitrogen, or sulfur compound NIPPON SHOKUBAI COMPANY, LTD. (JP) 2003-04-01 US disclosed
US-20010034300-A1 Reacting an alpha, beta unsaturated carboxylic acid ester with a heterocyclic oxygen nitrogen, or sulfur compound NIPPON SHOKUBAI COMPANY LTD. (JP) 2001-10-25 US disclosed
EP-1123915-A1 Process for producing alpha, beta-unsaturated carboxylic acid esters and catalyst for use in such process Nippon Shokubai Co., Ltd. (JP) 2001-08-16 EP disclosed