SCHEMBL27333392

SCHEMBL27333392

C=C(C(=O)CC(C)=O)C(=O)OCCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.43
THRB P10828 1/20 0.40
GAA P10253 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ALDH1A1 P00352 5/20 0.33
HCAR2 Q8TDS4 1/20 0.33
MGAM O43451 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
MAPT P10636 1/20 0.32
LMNA P02545 1/20 0.32
HPGD P15428 1/20 0.31
KDM4E B2RXH2 1/20 0.31
GLA P06280 1/20 0.31
ESR1 P03372 1/20 0.31
CHRM1 P11229 1/20 0.31
SLC6A2 P23975 1/20 0.31
KDR P35968 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
RAD52 P43351 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27739499 0.89 TSHR (0.53) TSHRTHRBALDH1A1HCAR2HPGD
SCHEMBL11253654 0.84 ALDH1A1 (0.44) TSHRTHRBGAASMN1; SMN2ALDH1A1
SCHEMBL5871999 0.81 TSHR (0.48) TSHRTHRBGAASMN1; SMN2ALDH1A1
SCHEMBL5408195 0.79 TSHR (0.48) TSHRTHRBGAASMN1; SMN2ALDH1A1
SCHEMBL2469328 0.79 TSHR (0.42) TSHRTHRBGAASMN1; SMN2ALDH1A1
SCHEMBL6657193 0.78 TSHR (0.42) TSHRTHRBGAASMN1; SMN2ALDH1A1
SCHEMBL27508659 0.77 ALDH1A1 (0.50) TSHRGAAALDH1A1MGAMSI
SCHEMBL28139815 0.76 TSHR (0.55) TSHRTHRBGAASMN1; SMN2ALDH1A1
SCHEMBL629109 0.75 TSHR (0.44) TSHRTHRBGAASMN1; SMN2ALDH1A1
SCHEMBL15536700 0.75 ALDH1A1 (0.47) TSHRTHRBGAASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101595142-B Fluorine-containing copolymer having excellent washing resistance and soil release agent DAIKIN IND LTD JP 2014-06-25 CN claimed
CN-101595142-A Fluorinated copolymer that has excellent washing resistance and stain remover DAIKIN IND LTD (JP) 2009-12-02 CN claimed
CN-105916895-B Improve the water-based paint compositions of open hour 欧尼克斯荷兰有限公司 2019-04-19 CN disclosed
CN-109641982-A Polymer with function imide group and the pigment dispersion and coating formed by it PPG工业俄亥俄公司 2019-04-16 CN disclosed
CN-104661763-B Method for forming multilayer coating film 关西涂料株式会社 2018-08-28 CN disclosed
CN-104797350-B Method for forming multilayer coating film 关西涂料株式会社 2017-09-15 CN disclosed
CN-104781327-B Thermosetting resin composition 帝斯曼知识产权资产管理有限公司 2017-05-17 CN disclosed
CN-106459673-A Methacrylate structural adhesive formulation and process for the use thereof 伊利诺斯工具制品有限公司 2017-02-22 CN disclosed
CN-105916895-A Waterborne coating composition with improved open time 树脂核动力工业有限公司 2016-08-31 CN disclosed
CN-104797350-A Method for forming multilayer coating film KANSAI PAINT CO LTD 2015-07-22 CN disclosed
CN-104781327-A Thermosetting resin composition DSM IP ASSETS BV 2015-07-15 CN disclosed
CN-1500704-A Composite positioning imaging element 伊斯曼柯达公司 2004-06-02 CN disclosed
CN-1427032-A Curable resin composition, process for preparing low polymer with acrylyl, substituted methacrylic acid radical and beta-dicarbonyl and its polymerizing process DAINIPPON INK & CHEMICALS (JP) 2003-07-02 CN disclosed
CN-1346853-A Aqueous paint composition with improved adhesiveness to brittle surface ROHM & HAAS (US) 2002-05-01 CN disclosed
CN-1339533-A Pigment dispenser for graft copolymer DU PONT (US) 2002-03-13 CN disclosed
CN-1276401-A Water-insoluble non-ionic graft copolymer adhesive DU PONT (US) 2000-12-13 CN disclosed
CN-1048997-C Utilizing metalions to compatibilize polymer blends ROHM & HAAS (US) 2000-02-02 CN disclosed
CN-1182767-A Paint composition with persistent storage stability and method for producing wearing-resistance coating from it ROHM & HAAS (US) 1998-05-27 CN disclosed
CN-1169448-A Extinction electrolytic-deposition coating composition HIPPON PAINT CO LTD (JP) 1998-01-07 CN disclosed
CN-1077465-A Make polymer blend compatible with metal ion ROHM & HAAS (US) 1993-10-20 CN disclosed