Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL8992010 | 1.00 | LMNA (1.00) | — | |
| Succinic Acid SCHEMBL3799615 | 1.00 | — | — | |
| Succinic Acid SCHEMBL1331252 | 1.00 | — | — | |
| Succinic Acid SCHEMBL4269135 | 1.00 | LMNA (1.00) | — | |
| Succinic Acid SCHEMBL24696 | 1.00 | LMNA (1.00) | — | |
| Succinic Acid SCHEMBL29808469 | 1.00 | — | — | |
| Succinic Acid SCHEMBL4269130 | 1.00 | LMNA (1.00) | — | |
| Succinic Acid SCHEMBL1331200 | 1.00 | — | — | |
| Succinic Acid SCHEMBL21867134 | 1.00 | LMNA (1.00) | — | |
| Succinic Acid SCHEMBL28176099 | 1.00 | LMNA (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 1293307 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410494-B1 | — | — | None | — | — | US | claimed |
| US-9974731-B2 | Method for producing functional lubricant and particulate material set used in the method | MEDICAL ARC CO., LTD. (JP) | 2018-05-22 | — | — | US | claimed |
| US-9975915-B1 | Crystalline forms of nicotinoyl ribosides, modified derivatives thereof, and phosphorylated analogs thereof, and methods of preparation thereof | THE QUEEN'S UNIVERSITY OF BELFAST (GB) | 2018-05-22 | — | — | US | claimed |
| US-9975847-B2 | Amino acid derivatives and their uses | JOHNSON & JOHNSON CONSUMER INC. (US) | 2018-05-22 | — | — | US | claimed |
| US-20180134743-A1 | EFFICIENT AND SCALABLE SYNTHESES OF NICOTINOYL RIBOSIDES AND REDUCED NICOTINOYL RIBOSIDES, MODIFIED DERIVATIVES THEREOF, PHOSPHORYLATED ANALOGS THEREOF, ADENYLYL DINUCLEOTIDE CONJUGATES THEREOF, AND NOVEL CRYSTALLINE FORMS THEREOF | THE QUEEN'S UNIVERSITY OF BELFAST (GB) | 2018-05-17 | — | — | US | claimed |
| US-20180134711-A1 | New stable formulations of 5,10-methylene-(6R)-tetrahydrofolic acid | Merck & Cie (CH) | 2018-05-17 | — | — | US | claimed |
| US-20180134658-A1 | SALTS AND PRODRUGS OF 1-METHYL-D-TRYPTOPHAN | LUMOS PHARMA, INC. | 2018-05-17 | — | — | US | claimed |
| WO-2018085918-A1 | NOVEL METHODS FOR CREATION OF SUB-MICRON BIOCARBON MATERIALS FROM BIOMASS AND THEIR FIELDS OF APPLICATION | UNIVERSITY OF GUELPH (CA) | 2018-05-17 | — | — | WO | claimed |
| WO-2018089773-A1 | SYSTEMS, DEVICES, AND METHODS FOR PERFORMING MEDICAL PROCEDURES IN THE INTESTINE | FRACTYL LABORATORIES, INC. (US) | 2018-05-17 | — | — | WO | claimed |
| WO-2018089465-A1 | NANOCARRIERS HAVING SURFACE CONJUGATED PEPTIDES AND USES THEREOF FOR SUSTAINED LOCAL RELEASE OF DRUGS | NORTHWESTERN UNIVERSITY (US) | 2018-05-17 | — | — | WO | claimed |
| US-3939193-A | D-Homosteroids | HOFFMANN-LA ROCHE INC. (US) | 1976-02-17 | — | — | US | claimed |
| US-3939145-A | VIRICIDE | STRATEGIC MEDICAL RESEARCH CORPORATION (US) | 1976-02-17 | — | — | US | claimed |
| US-3939146-A | VIRICIDE | STRATEGIC MEDICAL RESEARCH CORPORATION (US) | 1976-02-17 | — | — | US | claimed |
| US-3939204-A | IODO SUBST. DICARBOXYLIC ACID ANTILIDES | SCHERING AKTIENGESELLSCHAFT (DT) | 1976-02-17 | — | — | US | claimed |
| US-3937756-A | FIRE RETARDANT POLYESTER RESINS | JEFFERSON CHEMICAL COMPANY, INC. (US) | 1976-02-10 | — | — | US | claimed |
| US-3937673-A | DIELECTRICS | PHELPS DODGE INDUSTRIES, INC. (US) | 1976-02-10 | — | — | US | claimed |
| US-3936313-A | Method of preparing additives for calcium sulphate plaster | MODOKEMI AB (SW) | 1976-02-03 | — | — | US | claimed |
| US-3933658-A | PHOSPHATE ESTER AND SULFUR COMPOUND | GAF CORPORATION (US) | 1976-01-20 | — | — | US | claimed |
| US-3932363-A | PAPERMAKING | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-13 | — | — | US | claimed |
| US-3931142-A | Heterocyclic containing disazo compounds | CIBA-GEIGY AG (CH) | 1976-01-06 | — | — | US | claimed |