Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 3/20 | 0.33 |
| ▸ | IDO1 | P14902 | 3/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23788031 | 0.86 | HPGD (0.38) | HPGDALDH1A1APPCA9KDM4E | |
| SCHEMBL21369288 | 0.82 | KIF11 (0.52) | ACLYBRD4KIF11CA12CA9 | |
| SCHEMBL13523197 | 0.76 | HPGD (0.38) | HPGDAPPCA9GAAMAPT | |
| SCHEMBL20172614 | 0.74 | APP (0.33) | HPGDALDH1A1MCL1APPCA12 | |
| SCHEMBL24697528 | 0.72 | CTSC (0.36) | LTB4R | |
| SCHEMBL26012018 | 0.71 | EGLN1 (0.35) | HPGDALDH1A1HTR6MCL1BRD4 | |
| SCHEMBL24042269 | 0.70 | MAPT (0.57) | HPGDALDH1A1MAPT | |
| SCHEMBL24782869 | 0.70 | MAPT (0.33) | HPGDALDH1A1APPKDM4EMAPT | |
| SCHEMBL23615915 | 0.70 | APP (0.42) | HPGDALDH1A1HTR6APPKDM4E | |
| SCHEMBL18326852 | 0.70 | HTR6 (0.38) | HPGDALDH1A1HTR6MCL1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022232573-A1 | CERTAIN N-(1-CYANO-2-PHENYLETHYL)-1,4-OXAZEPANE-2-CARBOXAMIDES FOR TREATING CYSTIC FIBROSIS | INSMED INCORPORATED (US) | 2022-11-03 | — | — | WO | disclosed |