Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 10/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | BPTF | Q12830 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.37 |
| ▸ | BCHE | P06276 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30777931 | 1.00 | ACHE (0.43) | ACHEMAPK1MEN1KMT2ABPTF | |
| SCHEMBL1819184 | 0.95 | MAPK1 (0.47) | ACHEMAPK1MEN1KMT2ABPTF | |
| SCHEMBL29466623 | 0.95 | MAPK1 (0.47) | ACHEMAPK1MEN1KMT2ABPTF | |
| SCHEMBL16136206 | 0.93 | MAPK1 (0.46) | ACHEMAPK1MEN1KMT2ABPTF | |
| SCHEMBL15831715 | 0.93 | MAPK1 (0.46) | ACHEMAPK1MEN1KMT2ABPTF | |
| SCHEMBL23816987 | 0.93 | MAPK1 (0.46) | ACHEMAPK1MEN1KMT2ABPTF | |
| SCHEMBL31095398 | 0.93 | MAPK1 (0.46) | ACHEMAPK1MEN1KMT2ABPTF | |
| SCHEMBL21963334 | 0.78 | MAPK1 (0.48) | ACHEMAPK1MEN1KMT2ABPTF | |
| SCHEMBL1586850 | 0.77 | KDM4E (0.53) | ACHEMAPK1MEN1KMT2ABPTF | |
| SCHEMBL1069076 | 0.77 | KDM4E (0.41) | ACHEMAPK1MEN1KMT2ABPTF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 359 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11292854-A | — | — | None | — | — | JP | disclosed |
| US-12637458-B2 | Imidazo[1,2-a]pyridine compounds and their use in therapy | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2026-05-26 | — | — | US | disclosed |
| EP-4142732-B1 | METHODS OF USE FOR PYRIMIDINES AS FERROPORTIN INHIBITORS | GLOBAL BLOOD THERAPEUTICS INC (US) | 2026-04-22 | — | — | EP | disclosed |
| EP-4724430-A1 | CONDENSED AZINES AS INHIBITORS OF CYCLIC ADP RIBOSE HYDROLASE | Flagship Pioneering Innovations VI, LLC (US) | 2026-04-15 | — | — | EP | disclosed |
| US-20260092053-A1 | KHK INHIBITORS | GILEAD SCIENCES INC (US) | 2026-04-02 | — | — | US | disclosed |
| EP-4681774-A2 | KHK INHIBITORS | Gilead Sciences, Inc. (US) | 2026-01-21 | — | — | EP | disclosed |
| EP-4313967-B1 | KHK INHIBITORS | GILEAD SCIENCES INC (US) | 2025-11-12 | — | — | EP | disclosed |
| EP-4635949-A1 | SUBSTITUTED TETRAHYDROCYCLOPENTYL[C]PYRROLE DERIVATIVE, PREPARATION METHOD, INTERMEDIATE AND USE THEREOF | Jiangsu NHWA Pharmaceutical Co., Ltd (CN) | 2025-10-22 | — | — | EP | disclosed |
| US-12410160-B2 | KHK inhibitors | GILEAD SCIENCES, INC. (US) | 2025-09-09 | — | — | US | disclosed |
| US-20250230155-A1 | 7,8-DIHYDRO-5H-1,6-NAPHTHYRIDINE DERIVATIVES AS POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 FOR TREATING NEUROLOGICAL AND PSYCHIATRIC DISORDERS | VANDERBILT UNIVERSITY | 2025-07-17 | — | — | US | disclosed |
| US-20070027156-A1 | Crf antagonists and heterobicyclic compounds | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-02-01 | — | — | US | disclosed |
| EP-1666468-A1 | CRF ANTAGONISTS AND HETEROBICYCLIC COMPOUNDS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-06-07 | — | — | EP | disclosed |
| US-6951866-B2 | Bicyclic pyrimidine compounds and therapeutic use thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2005-10-04 | — | — | US | disclosed |
| EP-1110951-B1 | PYRIMIDINE DERIVATIVES | SUMITOMO PHARMA (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-20030105323-A1 | Pyrimidine derivative | SUMITOMO PHARMACEUTICALS COMPANY LIMITED | 2003-06-05 | — | — | US | disclosed |
| US-6458798-B1 | HAS AN INHIBITORY ACTIVITY OF PRODUCTION OF TH2 TYPE CYTOKINES SUCH AS IL-4, IL-5, ETC., AND IS USEFUL AS AN THERAPEUTIC AGENT FOR ALLERGIC DISEASES, AUTOIMMUNE DISEASES SUCH AS SYSTEMIC LUPUS ERYTHEMATHOSUS, ETC., AND ACQUIRED | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2002-10-01 | — | — | US | disclosed |
| EP-1110951-A1 | PYRIMIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-06-27 | — | — | EP | disclosed |
| JP-H11292854-A | NOVEL PYRIMIDINE DERIVATIVE | KANEBO LTD | 1999-10-26 | — | — | JP | disclosed |
| US-5416081-A | Antibiotics as bactericides | LUCKY LIMITED (KR) | 1995-05-16 | — | — | US | disclosed |
| EP-0604920-A1 | Novel cephalosporin compounds | LUCKY LTD. (KR) | 1994-07-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260092053-A1 | KHK INHIBITORS | KHK, SLC5A2, HK1 | ACHE 4271/4885MAPK1 398/4885MEN1 4138/4885 |
| US-12410160-B2 | KHK inhibitors | KHK, KHDRBS1, NADK | ACHE 4545/4885MAPK1 1141/4885MEN1 2989/4885 |
| US-20070027156-A1 | Crf antagonists and heterobicyclic compounds | CRHR2, CRHR1, CRH | ACHE 3319/4885MAPK1 2539/4885MEN1 3596/4885 |
| US-20030105323-A1 | Pyrimidine derivative | IL5, IL4, IL15 | ACHE 4681/4885MAPK1 639/4885MEN1 3390/4885 |
| US-12637458-B2 | Imidazo[1,2-a]pyridine compounds and their use in therapy | OGFR, CBR3, CBR1 | ACHE 1402/4885MAPK1 1047/4885MEN1 1503/4885 |
| US-20250230155-A1 | 7,8-DIHYDRO-5H-1,6-NAPHTHYRIDINE DERIVATIVES AS POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 FOR TREATING NEUROLOGICAL AND PSYCHIATRIC DISORDERS | CHRM5, CHRM4, CHRM1 | ACHE 22/4885MAPK1 1823/4885MEN1 2532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.