Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ASPH | Q12797 | 1/20 | 0.30 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15791914 | 0.94 | TDP1 (0.46) | TDP1HCAR2MDM2 | |
| SCHEMBL2469159 | 0.85 | TDP1 (0.58) | TDP1HCAR2FABP4FABP5ACHE | |
| SCHEMBL2466704 | 0.82 | NPSR1 (0.37) | TDP1KDM4E | |
| SCHEMBL2469819 | 0.78 | — | — | |
| SCHEMBL20955505 | 0.76 | TDP1 (0.41) | TDP1KDM4E | |
| SCHEMBL29928384 | 0.76 | TDP1 (0.69) | TDP1HCAR2MDM2KDM4EASPH | |
| SCHEMBL1424187 | 0.76 | TDP1 (0.69) | TDP1HCAR2MDM2KDM4EASPH | |
| SCHEMBL11027976 | 0.76 | DGAT1 (0.42) | TDP1 | |
| SCHEMBL19187069 | 0.75 | TDP1 (0.56) | TDP1HCAR2KDM4EASPHKDM8 | |
| SCHEMBL15791792 | 0.75 | TDP1 (0.45) | TDP1HCAR2MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102223795-A | Herbicide-safener combination | BAYER CROPSCIENCE AG | 2011-10-19 | — | — | CN | claimed |
| EP-2369927-A2 | HERBICIDE-SAFENER COMBINATION | Bayer CropScience AG (DE) | 2011-10-05 | — | — | EP | claimed |
| US-20100137136-A1 | HERBICIDE/SAFENER COMBINATION | BAYER CROPSCIENCE AG (DE) | 2010-06-03 | — | — | US | claimed |
| WO-2010060579-A2 | HERBICIDE-SAFENER COMBINATION | BAYER CROPSCIENCE AG (DE) | 2010-06-03 | — | — | WO | claimed |
| CN-102223795-A | Herbicide-safener combination | BAYER CROPSCIENCE AG | 2011-10-19 | — | — | CN | disclosed |
| EP-2369927-A2 | HERBICIDE-SAFENER COMBINATION | Bayer CropScience AG (DE) | 2011-10-05 | — | — | EP | disclosed |
| EP-2210492-A1 | Herbicide safener combination | Bayer CropScience AG (DE) | 2010-07-28 | — | — | EP | disclosed |
| US-20100137136-A1 | HERBICIDE/SAFENER COMBINATION | BAYER CROPSCIENCE AG (DE) | 2010-06-03 | — | — | US | disclosed |
| WO-2010060579-A2 | HERBICIDE-SAFENER COMBINATION | BAYER CROPSCIENCE AG (DE) | 2010-06-03 | — | — | WO | disclosed |
| WO-2006062979-A1 | HERBICIDAL 6-CYCLOPROPYL-SUBSTITUTE 4-AMINOPICOLINIC ACID DERIVATIVES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137136-A1 | HERBICIDE/SAFENER COMBINATION | DDT, GAP43, CYP2W1 | TDP1 471/4885HCAR2 749/4885FABP4 1319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.