Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 2/20 | 0.33 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | PLAU | P00749 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1424187 | 1.00 | TDP1 (0.69) | TDP1LMNAGAAMAPTATM | |
| SCHEMBL2342191 | 0.85 | TDP1 (0.69) | TDP1LMNAGAAMAPTATM | |
| SCHEMBL19187069 | 0.83 | TDP1 (0.56) | TDP1KEAP1NFE2L2KDM4EHCAR2 | |
| Picloram SCHEMBL8467014 | 0.82 | TDP1 (1.00) | TDP1LMNAGAAMAPTATM | |
| Picloram SCHEMBL29388079 | 0.82 | TDP1 (1.00) | TDP1LMNAGAAMAPTATM | |
| Picloram SCHEMBL13299 | 0.82 | TDP1 (1.00) | TDP1LMNAGAAMAPTATM | |
| SCHEMBL14354117 | 0.81 | TDP1 (0.50) | TDP1LMNAGAAKEAP1NFE2L2 | |
| SCHEMBL21806451 | 0.81 | TDP1 (0.55) | TDP1KEAP1NFE2L2KDM4EPLAU | |
| SCHEMBL30151452 | 0.81 | TDP1 (0.55) | TDP1KEAP1NFE2L2KDM4EPLAU | |
| SCHEMBL1424874 | 0.81 | TDP1 (0.55) | TDP1LMNAGAAMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458442-B1 | SYNTHESIS OF 6-ARYL-4-AMINOPICOLINATES AND 2-ARYL-6-AMINOPYRIMIDINE-4-CARBOXYLATES BY DIRECT SUZUKI COUPLING | CORTEVA AGRISCIENCE LLC (US) | 2022-12-28 | — | — | EP | claimed |
| CN-115298167-A | Improved synthesis of 6-aryl-4-aminopicolinates | 科迪华农业科技有限责任公司 | 2022-11-04 | — | — | CN | disclosed |