Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 3/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24698835 | 0.87 | GBA1 (0.47) | GBA1WNT3ATNKS2HRH2HRH3 | |
| SCHEMBL24698179 | 0.84 | WNT3A (0.36) | GBA1PDE10AWNT3ATNKS2HRH2 | |
| SCHEMBL24698834 | 0.81 | WNT3A (0.36) | GBA1WNT3ATNKS2HRH2HRH3 | |
| SCHEMBL24698426 | 0.80 | KARS1 (0.40) | GBA1HRH2HRH3KDM4EALDH1A1 | |
| SCHEMBL24698113 | 0.80 | HRH2 (0.36) | HRH2HRH3KDM4EMAPTLMNA | |
| SCHEMBL24699432 | 0.80 | HRH2 (0.38) | HRH2HRH3KDM4EMAPTLMNA | |
| SCHEMBL24698868 | 0.79 | PDE2A (0.38) | GBA1PDE10AHRH2HRH3KDM4E | |
| SCHEMBL24697726 | 0.77 | HRH2 (0.34) | HRH2HRH3KDM4EMAPTLMNA | |
| SCHEMBL24699404 | 0.76 | NISCH (0.35) | HRH2HRH3KDM4EMAPTLMNA | |
| SCHEMBL24697711 | 0.76 | KHK (0.43) | HRH2HRH3KDM4EMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212194-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2022-10-06 | — | — | WO | disclosed |