Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10335556 | 1.00 | TSHR (0.38) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL9784558 | 1.00 | TSHR (0.38) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL30212844 | 0.98 | GNAI3 (0.37) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL30212762 | 0.98 | GNAI3 (0.37) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL30213015 | 0.98 | GNAI3 (0.37) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL30212801 | 0.98 | GNAI3 (0.37) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL30213165 | 0.98 | GNAI3 (0.37) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL30212979 | 0.98 | GNAI3 (0.37) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL9784569 | 0.98 | GNAI3 (0.37) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL30212655 | 0.98 | GNAI3 (0.37) | TSHRTHRBGNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043636-B2 | Method for producing triarylorganoborates | COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) | 2024-07-23 | — | — | US | disclosed |
| US-20240002409-A1 | METHOD FOR PRODUCING TRIARYLORGANOBORATES | COVESTRO DEUTSCHLAND AG (DE) | 2024-01-04 | — | — | US | disclosed |
| US-11760765-B2 | Method for producing triarylorganoborates | COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) | 2023-09-19 | — | — | US | disclosed |
| US-11078218-B2 | Process for the production of triaryl organoborates | COVESTRO DEUTSCHLAND AG (DE) | 2021-08-03 | — | — | US | disclosed |
| US-20190276479-A1 | PROCESS FOR THE PRODUCTION OF TRIARYL ORGANOBORATES | COVESTRO DEUTSCHLAND AG (DE) | 2019-09-12 | — | — | US | disclosed |
| US-20190263838-A1 | METHOD FOR PRODUCING TRIARYLORGANOBORATES | COVESTRO DEUTSCHLAND AG (DE) | 2019-08-29 | — | — | US | disclosed |
| US-10001703-B2 | Photopolymer formulation for production of holographic media comprising borates with low TG | COVESTRO DEUTSCHLAND AG (DE) | 2018-06-19 | — | — | US | disclosed |
| US-20160252808-A1 | PHOTOPOLYMER FORMULATION FOR PRODUCTION OF HOLOGRAPHIC MEDIA COMPRISING BORATES WITH LOW TG | COVESTRO DEUTCHLAND AG (DE) | 2016-09-01 | — | — | US | disclosed |
| EP-3058423-A1 | PHOTOPOLYMER FORMULATION FOR PRODUCTION OF HOLOGRAPHIC MEDIA COMPRISING BORATES WITH LOW TG | Covestro Deutschland AG (DE) | 2016-08-24 | — | — | EP | disclosed |
| WO-2015055576-A1 | PHOTOPOLYMER FORMULATION FOR PRODUCTION OF HOLOGRAPHIC MEDIA COMPRISING BORATES WITH LOW TG | BAYER MATERIALSCIENCE AG (DE) | 2015-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240002409-A1 | METHOD FOR PRODUCING TRIARYLORGANOBORATES | KMO, COASY, CYP3A4 | TSHR 3184/4885THRB 1742/4885GNAI3 3199/4885 |
| US-11078218-B2 | Process for the production of triaryl organoborates | OR10J3, CYP4F3, CYP4B1 | TSHR 2354/4885THRB 430/4885GNAI3 2595/4885 |
| US-12043636-B2 | Method for producing triarylorganoborates | KMO, COASY, CYP3A4 | TSHR 3184/4885THRB 1742/4885GNAI3 3199/4885 |
| US-20190263838-A1 | METHOD FOR PRODUCING TRIARYLORGANOBORATES | CYP3A4, CYP3A43, CYP4B1 | TSHR 3341/4885THRB 1733/4885GNAI3 3506/4885 |
| US-10001703-B2 | Photopolymer formulation for production of holographic media comprising borates with low TG | PTGIS, TST, MACF1 | TSHR 4143/4885THRB 4523/4885GNAI3 788/4885 |
| US-20160252808-A1 | PHOTOPOLYMER FORMULATION FOR PRODUCTION OF HOLOGRAPHIC MEDIA COMPRISING BORATES WITH LOW TG | PTGIS, TST, MACF1 | TSHR 4143/4885THRB 4523/4885GNAI3 788/4885 |
| US-11760765-B2 | Method for producing triarylorganoborates | CYP3A4, CYP3A43, CYP4B1 | TSHR 3341/4885THRB 1733/4885GNAI3 3506/4885 |
| US-20190276479-A1 | PROCESS FOR THE PRODUCTION OF TRIARYL ORGANOBORATES | CYP1B1, CYP3A4, CYP4B1 | TSHR 3103/4885THRB 834/4885GNAI3 3172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.