Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 8/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | EIF4E | P06730 | 4/20 | 0.34 |
| ▸ | SMURF2 | Q9HAU4 | 1/20 | 0.33 |
| ▸ | SMURF1 | Q9HCE7 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16076583 | 0.90 | KMO (0.34) | PPARAKMOCYP3A4TDP1MEN1 | |
| SCHEMBL3329429 | 0.90 | CYP3A4 (0.37) | KMOCYP3A4TDP1EIF4EMDM2 | |
| SCHEMBL2465852 | 0.90 | PPARA (0.38) | PPARAKMOCYP3A4TDP1MEN1 | |
| SCHEMBL3328979 | 0.87 | KDM4E (0.40) | KMT2AHSD17B10 | |
| SCHEMBL16076603 | 0.86 | CYP3A4 (0.38) | KMOCYP3A4TDP1EIF4EHSP90AA1 | |
| SCHEMBL20727047 | 0.86 | EIF4E (0.36) | KMOCYP3A4TDP1EIF4ERARA | |
| SCHEMBL17623448 | 0.86 | KMO (0.35) | KMOCYP3A4TDP1EIF4E | |
| SCHEMBL16076572 | 0.86 | KMO (0.36) | PPARAKMOCYP3A4TDP1MEN1 | |
| SCHEMBL16076564 | 0.86 | KMO (0.36) | KMOCYP3A4TDP1EIF4EMDM2 | |
| SCHEMBL115379 | 0.85 | ALDH1A1 (0.40) | KMOCYP3A4HSD17B10HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2060566-B1 | Poly-substituted aryls | DOW AGROSCIENCES LLC (US) | 2016-06-08 | — | — | EP | claimed |
| EP-2975939-B1 | BROADLEAF CROP CONTROL WITH 6-ARYLPICOLINE CARBOXYLIC ACIDS, 2-ARYLPYRIMIDINE CARBOXYLIC ACIDS, OR SALTS OR ESTERS THEREOF | DOW AGROSCIENCES LLC (US) | 2020-08-05 | — | — | EP | disclosed |
| EP-2060566-B1 | Poly-substituted aryls | DOW AGROSCIENCES LLC (US) | 2016-06-08 | — | — | EP | disclosed |
| EP-2939541-A1 | HERBICIDE SAFENER COMBINATION | Bayer Intellectual Property GmbH (DE) | 2015-11-04 | — | — | EP | disclosed |
| EP-2939540-A1 | HERBICIDE SAFENER COMBINATION | Bayer Intellectual Property GmbH (DE) | 2015-11-04 | — | — | EP | disclosed |
| US-8962523-B2 | Herbicide/safener combination | BAYER CROPSCIENCE AG (DE) | 2015-02-24 | — | — | US | disclosed |
| US-20150051074-A1 | HERBICIDE/SAFENER COMBINATION | BAYER CROPSCIENCE AG (DE) | 2015-02-19 | — | — | US | disclosed |
| WO-2014158614-A1 | BROADLEAF CROP CONTROL WITH 6-ARYLPICOLINE CARBOXYLIC ACIDS, 2-ARYLPYRIMIDINE CARBOXYLIC ACIDS, OR SALTS OR ESTERS THEREOF | DOW AGROSCIENCES LLC (US) | 2014-10-02 | — | — | WO | disclosed |
| US-20140274715-A1 | BROADLEAF CROP CONTROL WITH 6-ARYLPICOLINE CARBOXYLIC ACIDS, 2-ARYLPYRIMIDINE CARBOXYLIC ACIDS, OR SALTS OR ESTERS THEREOF | DOW AGROSCIENCES LLC (US) | 2014-09-18 | — | — | US | disclosed |
| US-20140274715-A1 | BROADLEAF CROP CONTROL WITH 6-ARYLPICOLINE CARBOXYLIC ACIDS, 2-ARYLPYRIMIDINE CARBOXYLIC ACIDS, OR SALTS OR ESTERS THEREOF | DOW AGROSCIENCES LLC (US) | 2014-09-18 | — | — | US | disclosed |
| EP-2191719-A1 | Herbicide safener combination | Bayer CropScience AG (DE) | 2010-06-02 | — | — | EP | disclosed |
| EP-1973881-B1 | 6-(POLY-SUBSTITUTED ARYL)-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-10-28 | — | — | EP | disclosed |
| EP-2060566-A1 | Poly-substituted aryls | Dow AgroSciences LLC (US) | 2009-05-20 | — | — | EP | disclosed |
| US-7498468-B2 | 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2009-03-03 | — | — | US | disclosed |
| EP-1973881-A2 | 6-(POLY-SUBSTITUTED ARYL)-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | Dow Agrosciences LLC (US) | 2008-10-01 | — | — | EP | disclosed |
| US-20080051596-A1 | 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2008-02-28 | — | — | US | disclosed |
| US-20080045734-A1 | 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2008-02-21 | — | — | US | disclosed |
| US-7314849-B2 | 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2008-01-01 | — | — | US | disclosed |
| US-20070179060-A1 | 6-(Poly-substituted aryl)-4-aminopicolinates and their use as herbicides | CORTEVA AGRISCIENCE LLC | 2007-08-02 | — | — | US | disclosed |
| WO-2007082098-A2 | 6-(POLY-SUBSTITUTED ARYL)-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2007-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140274715-A1 | BROADLEAF CROP CONTROL WITH 6-ARYLPICOLINE CARBOXYLIC ACIDS, 2-ARYLPYRIMIDINE CARBOXYLIC ACIDS, OR SALTS OR ESTERS THEREOF | ABAT, NAT1, SLC7A5 | PPARA 29/4885KMO 446/4885CYP3A4 111/4885 |
| US-20080045734-A1 | 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides | AAAS, DDT, AADAC | PPARA 451/4885KMO 258/4885CYP3A4 589/4885 |
| US-20070179060-A1 | 6-(Poly-substituted aryl)-4-aminopicolinates and their use as herbicides | AAAS, DDT, AADAC | PPARA 451/4885KMO 258/4885CYP3A4 589/4885 |
| US-20080051596-A1 | 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides | AAAS, DDT, AADAC | PPARA 451/4885KMO 258/4885CYP3A4 589/4885 |
| US-20150051074-A1 | HERBICIDE/SAFENER COMBINATION | DDT, CYP2W1, GAP43 | PPARA 187/4885KMO 2242/4885CYP3A4 244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.