Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 12/20 | 0.36 |
| ▸ | KMO | O15229 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | EIF4E | P06730 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16076603 | 0.91 | CYP3A4 (0.38) | CYP3A4GRIN2BKMOTDP1KEAP1 | |
| SCHEMBL2469848 | 0.90 | PPARA (0.35) | CYP3A4KMOTDP1MDM2EIF4E | |
| SCHEMBL2469709 | 0.88 | CYP3A4 (0.40) | CYP3A4GRIN2BKMOTDP1KEAP1 | |
| SCHEMBL3332434 | 0.87 | ABL1 (0.37) | GRIN2BGRIN1 | |
| SCHEMBL20727047 | 0.86 | EIF4E (0.36) | CYP3A4KMOTDP1KEAP1NFE2L2 | |
| SCHEMBL3840682 | 0.85 | PTPN11 (0.37) | CYP3A4KMOTDP1 | |
| SCHEMBL16076561 | 0.85 | EIF4E (0.36) | CYP3A4KMOTDP1EIF4E | |
| SCHEMBL16076583 | 0.85 | KMO (0.34) | CYP3A4KMOTDP1MDM2EIF4E | |
| SCHEMBL2464665 | 0.84 | GRM2 (0.42) | CYP3A4KMOTDP1KEAP1NFE2L2 | |
| SCHEMBL2468069 | 0.83 | KMO (0.53) | CYP3A4GRIN2BKMOTDP1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2939540-A1 | HERBICIDE SAFENER COMBINATION | Bayer Intellectual Property GmbH (DE) | 2015-11-04 | — | — | EP | disclosed |
| EP-2939541-A1 | HERBICIDE SAFENER COMBINATION | Bayer Intellectual Property GmbH (DE) | 2015-11-04 | — | — | EP | disclosed |
| US-8962523-B2 | Herbicide/safener combination | BAYER CROPSCIENCE AG (DE) | 2015-02-24 | — | — | US | disclosed |
| US-20150051074-A1 | HERBICIDE/SAFENER COMBINATION | BAYER CROPSCIENCE AG (DE) | 2015-02-19 | — | — | US | disclosed |
| US-20100137137-A1 | HERBICIDE/SAFENER COMBINATION | BAYER CROPSCIENCE AG (DE) | 2010-06-03 | — | — | US | disclosed |
| EP-2191719-A1 | Herbicide safener combination | Bayer CropScience AG (DE) | 2010-06-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137137-A1 | HERBICIDE/SAFENER COMBINATION | DDT, CYP2W1, GAP43 | CYP3A4 244/4885GRIN2B 565/4885KMO 2242/4885 |
| US-20150051074-A1 | HERBICIDE/SAFENER COMBINATION | DDT, CYP2W1, GAP43 | CYP3A4 244/4885GRIN2B 565/4885KMO 2242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.