Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24698458 | 0.86 | HRH2 (0.36) | HCRTR1HCRTR2SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL24698728 | 0.86 | KDM4E (0.36) | SMN1; SMN2ALDH1A1KDM4EHSD17B10PIK3CA | |
| SCHEMBL24698500 | 0.85 | PIK3CA (0.34) | PIK3CA | |
| SCHEMBL24698174 | 0.83 | CFD (0.35) | HCRTR1HCRTR2CDK9 | |
| SCHEMBL24698900 | 0.83 | MEN1 (0.46) | SMN1; SMN2ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL24698482 | 0.80 | HRH3 (0.35) | ALDH1A1KDM4E | |
| SCHEMBL24697598 | 0.78 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL24697738 | 0.77 | HRH2 (0.38) | HCRTR1HCRTR2SMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL24698527 | 0.75 | IGF1R (0.38) | SMN1; SMN2ALDH1A1KDM4EHSD17B10PDE10A | |
| SCHEMBL24698300 | 0.75 | IGF1R (0.40) | ALDH1A1KDM4EPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212194-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2022-10-06 | — | — | WO | disclosed |