Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 2/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.34 |
| ▸ | VCP | P55072 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24698505 | 0.89 | CFD (0.37) | CFDVCPPRMT6 | |
| SCHEMBL24697738 | 0.89 | HRH2 (0.38) | VCPHCRTR1HCRTR2CDK9CCNT1 | |
| SCHEMBL24699003 | 0.86 | PRMT6 (0.39) | CFDAOC3VCPPRMT6 | |
| SCHEMBL30015765 | 0.84 | MTOR (0.34) | CFDVCPPRMT6NOS3NOS1 | |
| SCHEMBL24698173 | 0.84 | MTOR (0.34) | CFDVCPPRMT6NOS3NOS1 | |
| SCHEMBL24698951 | 0.83 | HCRTR1 (0.34) | HCRTR1HCRTR2CDK9 | |
| SCHEMBL24698098 | 0.82 | VCP (0.39) | VCPHCRTR1HCRTR2 | |
| SCHEMBL24698503 | 0.80 | CFD (0.36) | CFDVCPPRMT6NOS3NOS1 | |
| SCHEMBL24699012 | 0.80 | MTOR (0.41) | CFDVCPPRMT6NOS3NOS1 | |
| SCHEMBL30015464 | 0.80 | MTOR (0.41) | CFDVCPPRMT6NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212194-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2022-10-06 | — | — | WO | disclosed |