Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 3/20 | 0.35 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12206598 | 0.86 | HPGD (0.37) | PLA2G2APLA2G4APGRKDM4EMAPT | |
| SCHEMBL16639638 | 0.85 | PGR (0.33) | PLA2G2APLA2G4APGRKDM4EMAPT | |
| SCHEMBL21473909 | 0.84 | ALOX5 (0.35) | PLA2G2APLA2G4APGRPLA2G10 | |
| SCHEMBL21475616 | 0.83 | PLG (0.36) | PGR | |
| SCHEMBL16639291 | 0.83 | PGR (0.34) | PLA2G2APLA2G4APGRKDM4EMAPT | |
| SCHEMBL16639339 | 0.83 | PGR (0.30) | PLA2G2APLA2G4APGRKDM4EMAPT | |
| SCHEMBL23512135 | 0.82 | PGR (0.35) | PLA2G2APLA2G4APGRKDM4EMAPT | |
| SCHEMBL16639324 | 0.82 | KDM4E (0.31) | KDM4EMAPTHPGDALDH1A1KMT2A | |
| SCHEMBL21473896 | 0.81 | CDK4 (0.34) | — | |
| SCHEMBL22155608 | 0.81 | PLA2G2A (0.41) | PLA2G2APLA2G4AKDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11512039-B2 | Aromatic amine derivatives, preparation methods therefor, and uses thereof | GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) | 2022-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11512039-B2 | Aromatic amine derivatives, preparation methods therefor, and uses thereof | SLC7A1, WEE1, SLC7A5 | PLA2G2A 4400/4885PLA2G4A 4459/4885PGR 2606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.