Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | MMP13 | P45452 | 6/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | IGF1R | P08069 | 2/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24698198 | 0.88 | KDM4E (0.36) | DRD2HTR2AMMP13KDM4ESMN1; SMN2 | |
| SCHEMBL24699086 | 0.84 | MTOR (0.37) | DRD2HTR2AMMP13ACVRL1KDM4E | |
| SCHEMBL30016011 | 0.84 | MTOR (0.37) | DRD2HTR2AMMP13ACVRL1KDM4E | |
| SCHEMBL24698205 | 0.81 | KHK (0.34) | DRD2HTR2AMMP13ACVRL1 | |
| SCHEMBL24698524 | 0.81 | HRH2 (0.39) | PIK3CAIGF1RGBA1KDM4EALDH1A1 | |
| SCHEMBL24699042 | 0.81 | CYP11B2 (0.48) | KDM4E | |
| SCHEMBL24699476 | 0.80 | GBA1 (0.39) | PIK3CAGBA1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL24698813 | 0.77 | IGF1R (0.37) | DRD2HTR2AIGF1RGBA1KDM4E | |
| SCHEMBL24697795 | 0.76 | ALDH1A1 (0.40) | PIK3CAIGF1RGBA1KDM4EALDH1A1 | |
| SCHEMBL24699481 | 0.76 | GBA1 (0.39) | PIK3CAIGF1RGBA1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212194-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2022-10-06 | — | — | WO | disclosed |