Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 9/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 8/20 | 0.48 |
| ▸ | KDM1A | O60341 | 6/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24698161 | 0.86 | CYP11B2 (0.39) | CYP11B2KDM4EADORA2A | |
| SCHEMBL24699037 | 0.84 | MTOR (0.44) | CYP11B2CYP11B1KDM1A | |
| SCHEMBL30016357 | 0.84 | MTOR (0.44) | CYP11B2CYP11B1KDM1A | |
| SCHEMBL24699497 | 0.83 | HSD17B10 (0.43) | KDM4E | |
| SCHEMBL24699083 | 0.81 | DRD2 (0.38) | KDM4E | |
| SCHEMBL24699476 | 0.79 | GBA1 (0.39) | KDM1AKDM4EPDE10A | |
| SCHEMBL24698813 | 0.78 | IGF1R (0.37) | KDM4E | |
| SCHEMBL24697795 | 0.75 | ALDH1A1 (0.40) | KDM4E | |
| SCHEMBL24699477 | 0.75 | ALDH1A1 (0.47) | KDM4E | |
| SCHEMBL24698171 | 0.74 | ALDH1A1 (0.54) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212194-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2022-10-06 | — | — | WO | disclosed |