Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | FPR1 | P21462 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30015772 | 1.00 | MEN1 (0.39) | MEN1KMT2AMTORKDM4EMAPT | |
| SCHEMBL24698168 | 0.88 | HRH2 (0.43) | MEN1KMT2AKDM4EMAPTHRH2 | |
| SCHEMBL29134842 | 0.84 | PIK3CA (0.41) | MTORMAP3K12HRH2HRH3 | |
| SCHEMBL24699439 | 0.84 | PIK3CA (0.41) | MTORMAP3K12HRH2HRH3 | |
| SCHEMBL24698018 | 0.82 | HRH3 (0.48) | MEN1KMT2AMTORKDM4EMAPT | |
| SCHEMBL30015307 | 0.82 | HRH3 (0.48) | MEN1KMT2AMTORKDM4EMAPT | |
| SCHEMBL24697950 | 0.81 | MAP3K12 (0.49) | MAP3K12 | |
| SCHEMBL24697693 | 0.79 | MEN1 (0.34) | MEN1KMT2AKDM4EMAP3K12HRH2 | |
| SCHEMBL24698700 | 0.79 | MTOR (0.38) | MTORKDM4EHRH3 | |
| SCHEMBL30017019 | 0.79 | MTOR (0.38) | MTORKDM4EHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212194-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2022-10-06 | — | — | WO | disclosed |