Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 15/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 14/20 | 0.41 |
| ▸ | MTOR | P42345 | 9/20 | 0.41 |
| ▸ | RICTOR | Q6R327 | 6/20 | 0.41 |
| ▸ | RPTOR | Q8N122 | 6/20 | 0.41 |
| ▸ | MAPKAP1 | Q9BPZ7 | 6/20 | 0.41 |
| ▸ | MLST8 | Q9BVC4 | 6/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.39 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24699439 | 1.00 | PIK3CA (0.41) | PIK3CAPIK3R1MTORRICTORRPTOR | |
| SCHEMBL24697950 | 0.88 | MAP3K12 (0.49) | PIK3CAPIK3R1MAP3K12 | |
| SCHEMBL30015772 | 0.84 | MEN1 (0.39) | MTORMAP3K12HRH2HRH3 | |
| SCHEMBL24699331 | 0.84 | MEN1 (0.39) | MTORMAP3K12HRH2HRH3 | |
| SCHEMBL29134430 | 0.83 | BACE1 (0.39) | PIK3CAMTORPIK3CDPIK3CBPIK3CG | |
| SCHEMBL30016204 | 0.83 | BACE1 (0.39) | PIK3CAMTORPIK3CDPIK3CBPIK3CG | |
| SCHEMBL24698935 | 0.83 | BACE1 (0.39) | PIK3CAMTORPIK3CDPIK3CBPIK3CG | |
| SCHEMBL24699440 | 0.82 | PIK3CA (0.49) | PIK3CAPIK3R1MTORRICTORRPTOR | |
| SCHEMBL24697693 | 0.81 | MEN1 (0.34) | PIK3CAPIK3R1MAP3K12HRH2HRH3 | |
| SCHEMBL24697798 | 0.81 | PDK1 (0.40) | MTORHRH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120429-A | KHK inhibitor | 吉利德科学公司 | 2023-11-24 | — | — | CN | disclosed |