Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TKT | P29401 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9334644 | 0.88 | L3MBTL1 (0.47) | ALDH1A1L3MBTL1HSD17B10TKTCXCR4 | |
| SCHEMBL6562804 | 0.88 | GRM5 (0.46) | GRM5ALDH1A1L3MBTL1ADRA2AADRA2B | |
| SCHEMBL5108741 | 0.87 | L3MBTL1 (0.52) | GRM5ALDH1A1L3MBTL1HSD17B10ADRA2A | |
| SCHEMBL28490737 | 0.87 | L3MBTL1 (0.42) | ALDH1A1L3MBTL1HSD17B10TKTCXCR4 | |
| Ammonia Solution, Strong SCHEMBL27809045 | 0.86 | GRM5 (0.45) | GRM5ALDH1A1L3MBTL1ADRA2AADRA2B | |
| Water SCHEMBL27859416 | 0.86 | GRM5 (0.45) | GRM5ALDH1A1L3MBTL1ADRA2AADRA2B | |
| SCHEMBL5102711 | 0.83 | L3MBTL1 (0.47) | GRM5ALDH1A1L3MBTL1HSD17B10KDM4E | |
| SCHEMBL13073704 | 0.83 | GRM5 (0.43) | GRM5ALDH1A1L3MBTL1ADRA2AADRA2B | |
| SCHEMBL13964873 | 0.82 | GRM5 (0.49) | GRM5ALDH1A1L3MBTL1ADRA2AADRA2B | |
| SCHEMBL21618225 | 0.82 | L3MBTL1 (0.50) | ALDH1A1L3MBTL1HSD17B10TKTCXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4046988-A1 | 2-FORMYL-3-HYDROXYPHENYLOXYMETHYL COMPOUNDS CAPABLE OF MODULATING HEMOGLOBIN | Global Blood Therapeutics, Inc. (US) | 2022-08-24 | — | — | EP | disclosed |