Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | NMT1 | P30419 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL27859416 | 0.98 | GRM5 (0.45) | GRM5ADRA2BADRA2CADRA2APDE3B | |
| Ammonia Solution, Strong SCHEMBL27809045 | 0.98 | GRM5 (0.45) | GRM5ADRA2BADRA2CADRA2APDE3B | |
| SCHEMBL13073704 | 0.90 | GRM5 (0.43) | GRM5ADRA2BADRA2CADRA2AALDH1A1 | |
| SCHEMBL13964173 | 0.89 | GRM5 (0.41) | GRM5ADRA2BADRA2CADRA2APDE3B | |
| SCHEMBL13964873 | 0.89 | GRM5 (0.49) | GRM5ADRA2BADRA2CADRA2APDE3B | |
| Formamide SCHEMBL27772867 | 0.89 | GRM5 (0.40) | GRM5ADRA2BADRA2CADRA2APDE3B | |
| SCHEMBL24701183 | 0.88 | GRM5 (0.42) | GRM5ADRA2BADRA2CADRA2ANMT1 | |
| SCHEMBL20818101 | 0.86 | GRM5 (0.40) | GRM5ADRA2BADRA2CADRA2APDE3B | |
| SCHEMBL5102711 | 0.86 | L3MBTL1 (0.47) | GRM5PDE3BPDE3ANMT1ALDH1A1 | |
| SCHEMBL2090444 | 0.86 | GRM5 (0.43) | GRM5ADRA2BADRA2CADRA2APDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100366605-C | Compounds to treat alzheimer's disease | ELAN PHARM INC (US) | 2008-02-06 | — | — | CN | claimed |
| CN-1447789-A | Compounds for treating alzheimer's disease | ELAN PHARM INC (US) | 2003-10-08 | — | — | CN | claimed |
| CN-112996788-B | Anthelmintic heterocyclic compounds | 勃林格殷格翰动物保健美国公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-116897044-A | Parasiticidal rings comprising isoxazoline compounds | 勃林格殷格翰动物保健有限公司 | 2023-10-17 | — | — | CN | disclosed |
| CN-110403937-A | Parasiticidal oral veterinary compositions comprising systemically acting active agents, methods and uses thereof | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC | 2019-11-05 | — | — | CN | disclosed |
| CN-105884693-B | The composition of Parasiticidal comprising benzimidizole derivatives, method and purposes | Merria Co., Ltd. (US) | 2019-11-01 | — | — | CN | disclosed |
| CN-110381738-A | Pesticide and Parasiticidal vinyl isoxazoline compound | 勃林格殷格翰动物保健美国公司 | 2019-10-25 | — | — | CN | disclosed |
| CN-110251509-A | Parasiticidal oral veterinary compositions comprising systemically acting active agents, methods and uses thereof | 勃林格殷格翰动物保健美国公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-110167921-A | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | 勃林格殷格翰动物保健美国公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-109068651-A | Antiparasitic isoxazoline compounds, long-acting injectable formulations containing them, methods and uses thereof | 梅里亚股份有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-105232529-B | The Moxidectin preparaton and Moxidectin crystal form of long-acting injectable | 梅里亚有限公司 | 2018-11-23 | — | — | CN | disclosed |
| US-7834182-B2 | histamine H3 receptor antagonists; metabolic disorders, sleep disorders, cardiovascular disorders, alcoholism, drug addiction, memory disorders, Alzheimer's, Parkinson's disease; 2-(4-piperidinylpiperidinyl)pyrimidine compounds such as 2-[(4-piperidin-1-yl)piperidin-1-yl]-5-(3-pyridyl)pyrimidine | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-11-16 | — | — | US | disclosed |
| US-20090203710-A1 | Novel piperidine derivative | MSD K.K. (JP) | 2009-08-13 | — | — | US | disclosed |
| CN-100366605-C | Compounds to treat alzheimer's disease | ELAN PHARM INC (US) | 2008-02-06 | — | — | CN | disclosed |
| US-20070105901-A1 | Novel piperidine derivative | MSD K.K. (JP) | 2007-05-10 | — | — | US | disclosed |
| CN-1612871-A | Processes and intermediates for preparing benzyl epoxides | ELAN PHARM INC (US) | 2005-05-04 | — | — | CN | disclosed |
| EP-0891970-B1 | Process for producing alkenylsubstituted pyridine derivatives | SUMITOMO CHEMICAL CO (JP) | 2004-10-13 | — | — | EP | disclosed |
| CN-1447789-A | Compounds for treating alzheimer's disease | ELAN PHARM INC (US) | 2003-10-08 | — | — | CN | disclosed |
| US-6008364-A | Process for producing alkenyl--substituted pyridine derivative | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-12-28 | — | — | US | disclosed |
| EP-0891970-A1 | Process for producing alkenylsubstituted pyridine derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1999-01-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105901-A1 | Novel piperidine derivative | HRH3, OPRM1, OPRK1 | GRM5 280/4885ADRA2B 153/4885ADRA2C 130/4885 |
| US-20090203710-A1 | Novel piperidine derivative | HRH3, OPRM1, HRH4 | GRM5 238/4885ADRA2B 144/4885ADRA2C 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.