Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | TKT | P29401 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21618225 | 0.89 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1HSD17B10KDM4ETKT | |
| SCHEMBL31303512 | 0.89 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1HSD17B10KDM4ETKT | |
| SCHEMBL18995127 | 0.89 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1HSD17B10KDM4ETKT | |
| SCHEMBL24701183 | 0.88 | GRM5 (0.42) | L3MBTL1ALDH1A1HSD17B10KDM4ETKT | |
| SCHEMBL28490737 | 0.86 | L3MBTL1 (0.42) | L3MBTL1ALDH1A1HSD17B10KDM4ETKT | |
| SCHEMBL10696175 | 0.82 | KDM4E (0.49) | ALDH1A1KDM4ENPC1GAARAB9A | |
| SCHEMBL27895802 | 0.81 | ALDH1A1 (0.39) | L3MBTL1ALDH1A1HSD17B10KDM4ETKT | |
| SCHEMBL31692108 | 0.80 | KDM4E (0.39) | L3MBTL1ALDH1A1KDM4ETKTCYP1A2 | |
| SCHEMBL31308700 | 0.78 | ALDH1A1 (0.69) | L3MBTL1ALDH1A1HSD17B10KDM4EMAPT | |
| SCHEMBL1431751 | 0.78 | L3MBTL1 (0.42) | L3MBTL1ALDH1A1HSD17B10KDM4ETKT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105093874-A | Electrophotographic member, process cartridge, and electrophotographic apparatus | CANON KK | 2015-11-25 | — | — | CN | disclosed |
| US-20090312306-A1 | TETRAHYDRO-5H-PYRIDO[2,3-D]AZEPINES AS 5-HT2C LIGANDS | CASCADE THERAPEUTICS INC. (CA) | 2009-12-17 | — | — | US | disclosed |
| US-5280096-A | Optically active polymer | UNIVERSITY OF NEW MEXICO (US) | 1994-01-18 | — | — | US | disclosed |
| US-5166062-A | Reaction a mixture of acyl esters with enzymes and selectively deacylating followed by separation | UNIVERSITY OF NEW MEXICO (US) | 1992-11-24 | — | — | US | disclosed |
| US-4477673-A | Process for the preparation of substituted divinylpyridines and novel substituted divinylpyridines | CIBA-GEIGY CORPORATION (US) | 1984-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312306-A1 | TETRAHYDRO-5H-PYRIDO[2,3-D]AZEPINES AS 5-HT2C LIGANDS | HTR2C, HTR2A, HTR5A | L3MBTL1 3929/4885ALDH1A1 1316/4885HSD17B10 1952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.