SCHEMBL24701273

SCHEMBL24701273

CCC(=O)C(C)(C)CC(C)(C)CN1C(=O)CCC1=O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
BLM P54132 1/20 0.32
WRN Q14191 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26696359 0.83 BLM (0.33) TSHRBLMWRN
SCHEMBL23900609 0.80 BLM (0.42) BLMWRN
SCHEMBL27251982 0.79 BLM (0.31) BLMWRN
SCHEMBL21345397 0.76 BLM (0.39) BLMWRN
SCHEMBL9724425 0.71 SMN1; SMN2 (0.35) TSHR
SCHEMBL15541204 0.69 CYP3A4 (0.44) BLMWRN
SCHEMBL24701448 0.67
SCHEMBL12228960 0.67 BLM (0.34) TSHRBLMWRN
SCHEMBL24521652 0.66 KDM4E (0.41)
SCHEMBL21067598 0.66 ALDH1A1 (0.33) BLMWRN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022254377-A1 NEODEGRADER-ANTI-CD33 ANTIBODY CONJUGATES ORUM THERAPEUTICS, INC. (KR) 2022-12-08 WO disclosed