Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.31 |
| ▸ | ACLY | P53396 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32670255 | 0.77 | RAB9A (0.32) | SMN1; SMN2RAB9ATSHR | |
| SCHEMBL12228960 | 0.75 | BLM (0.34) | TSHRPOLBMEN1KMT2A | |
| SCHEMBL26696359 | 0.73 | BLM (0.33) | TSHR | |
| SCHEMBL26961916 | 0.73 | TSHR (0.49) | TSHRPOLBALDH1A1ALOX12KMT2A | |
| SCHEMBL3690441 | 0.72 | HTR2A (0.39) | HTR2AHRH1HTR2C | |
| SCHEMBL29270763 | 0.72 | PER2 (0.48) | SMN1; SMN2TSHRKMT2AHTT | |
| SCHEMBL24701273 | 0.71 | TSHR (0.32) | TSHR | |
| SCHEMBL27251982 | 0.70 | BLM (0.31) | — | |
| SCHEMBL28655810 | 0.69 | CA12 (0.55) | SMN1; SMN2RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL18627863 | 0.69 | HTR2A (0.35) | HTR2AHRH1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153173-A | Administering to humans and animals to modulate immunoresponse | PLIVA FARMACEUTSKA (YU) | 1992-10-06 | — | — | US | disclosed |
| EP-0390039-A2 | N-Acyl derivatives of the peptidoglycan monomer, pharmaceutically acceptable salts thereof, their preparation and use in the manufacture of immunomodulators and immunoadjuvants | PLIVA FARMACEUTSKA, KEMIJSKA, PREHRAMBENA I KOZMETICKA INDUSTRIJA S P.O. (YU) | 1990-10-03 | — | — | EP | disclosed |