⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23900597 | 0.84 | — | — | |
| SCHEMBL23900561 | 0.76 | — | — | |
| SCHEMBL24701273 | 0.67 | TSHR (0.32) | — | |
| SCHEMBL26696359 | 0.64 | BLM (0.33) | — | |
| SCHEMBL23900852 | 0.63 | — | — | |
| SCHEMBL23900651 | 0.62 | HTR1A (0.35) | — | |
| SCHEMBL25910307 | 0.61 | KDM4E (0.32) | — | |
| SCHEMBL23900482 | 0.60 | — | — | |
| SCHEMBL21907862 | 0.59 | GLRA1 (0.32) | — | |
| SCHEMBL23900389 | 0.58 | MAPK1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024075080-A1 | NEODEGRADER CONJUGATES | ORUM THERAPEUTICS, INC. (KR) | 2024-04-11 | — | — | WO | disclosed |
| WO-2022254377-A1 | NEODEGRADER-ANTI-CD33 ANTIBODY CONJUGATES | ORUM THERAPEUTICS, INC. (KR) | 2022-12-08 | — | — | WO | disclosed |