Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.47 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.47 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | SRC | P12931 | 2/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29487215 | 1.00 | PI4KA (0.47) | PI4KAPI4K2BPI4K2API4KBTLR7 | |
| SCHEMBL130702 | 0.75 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBTLR7 | |
| SCHEMBL4409891 | 0.74 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL130798 | 0.73 | PI4KA (0.53) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL29685062 | 0.73 | PDE2A (0.60) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL128577 | 0.73 | PI4KA (0.53) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL130521 | 0.73 | PDE2A (0.60) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL21282826 | 0.70 | PI4KA (0.50) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL29385938 | 0.70 | PI4KA (0.50) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL26973527 | 0.70 | PI4KA (0.50) | PI4KAPI4K2BPI4K2API4KBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752506-B1 | PYRIMIDINE DERIVATIVES FOR PREVENTION AND TREATMENT OF BACTERIAL INFECTIONS | UNIV LIEGE (BE) | 2022-12-14 | — | — | EP | disclosed |