Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.50 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.50 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.50 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | BCDIN3D | Q7Z5W3 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL130702 | 0.78 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBMEN1 | |
| SCHEMBL4409891 | 0.77 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBMEN1 | |
| SCHEMBL130521 | 0.75 | PDE2A (0.60) | PI4KAPI4K2BPI4K2API4KBMEN1 | |
| SCHEMBL130798 | 0.75 | PI4KA (0.53) | PI4KAPI4K2BPI4K2API4KBMEN1 | |
| SCHEMBL128577 | 0.75 | PI4KA (0.53) | PI4KAPI4K2BPI4K2API4KBMEN1 | |
| SCHEMBL29685062 | 0.75 | PDE2A (0.60) | PI4KAPI4K2BPI4K2API4KBMEN1 | |
| SCHEMBL13082325 | 0.72 | MEN1 (0.46) | PI4KAPI4K2BPI4K2API4KBMEN1 | |
| SCHEMBL29385938 | 0.72 | PI4KA (0.50) | PI4KAPI4K2BPI4K2API4KBMEN1 | |
| SCHEMBL21282826 | 0.72 | PI4KA (0.50) | PI4KAPI4K2BPI4K2API4KBMEN1 | |
| SCHEMBL24701697 | 0.70 | PI4KA (0.47) | PI4KAPI4K2BPI4K2API4KBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858907-B2 | Kinase modulators | RHIZEN PHARMACEUTICALS AG (CH) | 2024-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11858907-B2 | Kinase modulators | RPS6KA1, RPS6KA2, PRKAR2A | PI4KA 156/4885PI4K2B 140/4885PI4K2A 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.