SCHEMBL247037

SCHEMBL247037

O=C1C=C(N2CCOCC2)C(=O)c2ccccc21

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.79
TDP2 O95551 4/20 0.79
NSD2 O96028 4/20 0.79
MEN1 O00255 4/20 0.79
APAF1 O14727 4/20 0.79
NPC1 O15118 4/20 0.79
HKDC1 Q2TB90 3/20 0.79
BLM P54132 3/20 0.79
RAB9A P51151 2/20 0.79
ATM Q13315 2/20 0.79
GALK1 P51570 1/20 0.79
NOD2 Q9HC29 1/20 0.79
ATG4B Q9Y4P1 1/20 0.79
S100A4 P26447 2/20 0.63
DNMT1 P26358 1/20 0.59
MAPT P10636 9/20 0.56
SMN1; SMN2 Q16637 5/20 0.56
HTT P42858 4/20 0.56
TP53 P04637 2/20 0.56
STAT3 P40763 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30601628 0.88 APAF1 (1.00) KMT2ATDP2NSD2MEN1APAF1
SCHEMBL4647391 0.88 APAF1 (1.00) KMT2ATDP2NSD2MEN1APAF1
SCHEMBL14566962 0.84 KMT2A (0.61) KMT2ATDP2NSD2MEN1APAF1
SCHEMBL4876610 0.84 APAF1 (0.74) KMT2ATDP2NSD2MEN1APAF1
SCHEMBL31290245 0.84 APAF1 (0.74) KMT2ATDP2NSD2MEN1APAF1
SCHEMBL31290115 0.82 APAF1 (0.77) KMT2ATDP2NSD2MEN1APAF1
SCHEMBL249168 0.82 APAF1 (0.77) KMT2ATDP2NSD2MEN1APAF1
SCHEMBL17249923 0.79 DNMT1 (0.64) KMT2ATDP2NSD2MEN1APAF1
SCHEMBL246623 0.79 DNMT1 (0.59) KMT2ATDP2NSD2MEN1APAF1
SCHEMBL10446509 0.78 TDP2 (0.73) KMT2ATDP2NSD2MEN1APAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4324852-A REDOX COUPLES EASTMAN KODAK COMPANY (US) 1982-04-13 US claimed
US-4201588-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, CARBAZIDES OR QUINONES AS PHOTOREDUCTANT; EXTERNAL HYDROGEN SOURCE EASTMAN KODAK COMPANY (US) 1980-05-06 US claimed
US-4195998-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, QUINONE OR CARBAZIDE PHOTOREDUCTANT EASTMAN KODAK COMPANY (US) 1980-04-01 US claimed
US-20180128767-A1 Small Volume In Vitro Analyte Sensor ABBOTT DIABETES CARE INC. (US) 2018-05-10 US disclosed
US-9891185-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2018-02-13 US disclosed
US-9662057-B2 Integrated sample acquisition and analyte measurement method ABBOTT DIABETES CARE INC. (US) 2017-05-30 US disclosed
US-20160334356-A1 Small Volume In Vitro Analyte Sensor THERASENSE, INC. 2016-11-17 US disclosed
US-20160235350-A1 Integrated Sample Acquisition and Analyte Measurement Device THERASENSE, INC. 2016-08-18 US disclosed
US-9341591-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2016-05-17 US disclosed
US-9316609-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2016-04-19 US disclosed
US-9291592-B2 Small volume in vitro analyte sensor ABBOTT DIABETES CARE INC. (US) 2016-03-22 US disclosed
US-4334005-A Transition metal photoreduction systems and processes EASTMAN KODAK COMPANY (US) 1982-06-08 US disclosed
US-4332884-A USING A DIOXIME CHELATING AGENT RICOH CO., LTD. (JP) 1982-06-01 US disclosed
US-4324852-A REDOX COUPLES EASTMAN KODAK COMPANY (US) 1982-04-13 US disclosed
US-4315068-A CONTAINING A COBALT-AMMINE COMPLEX AND A DIOXIME OR A BISIMIDAZOLIN-3-ONE CHELATING AGENT; STABILITY; COLOR DILMS RICOH CO., LTD. (JP) 1982-02-09 US disclosed
US-4314019-A NONSILVER PHOTOGRAPHY; COBALT AMMINE COMPLEXES) QUINONE REDUCING AGENTS EASTMAN KODAK COMPANY (US) 1982-02-02 US disclosed
US-4306014-A AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM RICOH CO., LTD. (JP) 1981-12-15 US disclosed
US-4201588-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, CARBAZIDES OR QUINONES AS PHOTOREDUCTANT; EXTERNAL HYDROGEN SOURCE EASTMAN KODAK COMPANY (US) 1980-05-06 US disclosed
US-4195998-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, QUINONE OR CARBAZIDE PHOTOREDUCTANT EASTMAN KODAK COMPANY (US) 1980-04-01 US disclosed
US-4171221-A NONSILVER PHOTOGTAPHY EASTMAN KODAK COMPANY (US) 1979-10-16 US disclosed