Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 4/20 | 0.74 |
| ▸ | TDP2 | O95551 | 2/20 | 0.74 |
| ▸ | NSD2 | O96028 | 2/20 | 0.74 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.74 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | GALK1 | P51570 | 1/20 | 0.56 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.56 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | RAF1 | P04049 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31290245 | 1.00 | APAF1 (0.74) | APAF1TDP2NSD2HKDC1DNMT1 | |
| SCHEMBL249168 | 0.98 | APAF1 (0.77) | APAF1TDP2NSD2HKDC1DNMT1 | |
| SCHEMBL31290115 | 0.98 | APAF1 (0.77) | APAF1TDP2NSD2HKDC1DNMT1 | |
| SCHEMBL7260223 | 0.85 | APAF1 (1.00) | APAF1TDP2NSD2HKDC1DNMT1 | |
| SCHEMBL247037 | 0.84 | KMT2A (0.79) | APAF1TDP2NSD2HKDC1DNMT1 | |
| SCHEMBL17249923 | 0.84 | DNMT1 (0.64) | APAF1TDP2NSD2HKDC1DNMT1 | |
| SCHEMBL246623 | 0.84 | DNMT1 (0.59) | APAF1TDP2NSD2HKDC1DNMT1 | |
| SCHEMBL14566964 | 0.81 | APAF1 (0.59) | APAF1TDP2NSD2HKDC1DNMT1 | |
| SCHEMBL29203715 | 0.79 | APAF1 (0.62) | APAF1TDP2NSD2HKDC1DNMT1 | |
| SCHEMBL20043023 | 0.77 | CHRNA7 (0.51) | APAF1TDP2NSD2HKDC1DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324852-A | REDOX COUPLES | EASTMAN KODAK COMPANY (US) | 1982-04-13 | — | — | US | claimed |
| US-4201588-A | NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, CARBAZIDES OR QUINONES AS PHOTOREDUCTANT; EXTERNAL HYDROGEN SOURCE | EASTMAN KODAK COMPANY (US) | 1980-05-06 | — | — | US | claimed |
| US-4195998-A | NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, QUINONE OR CARBAZIDE PHOTOREDUCTANT | EASTMAN KODAK COMPANY (US) | 1980-04-01 | — | — | US | claimed |
| US-20180099917-A1 | REVERSIBLY REDUCIBLE MATERIALS AND USE THEREOF | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2018-04-12 | — | — | US | disclosed |
| US-20180099917-A1 | REVERSIBLY REDUCIBLE MATERIALS AND USE THEREOF | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2018-04-12 | — | — | US | disclosed |
| US-8513437-B2 | Pyrrolidino-1,4-naphthoquinone deriviatives and their use for treating malignancies and cardiovascular diseases | BEN GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IS) | 2013-08-20 | — | — | US | disclosed |
| US-20080300274-A1 | Novel Pyrrolidino-1,4-Naphthoquinone Deriviatives and their Use for Treating Malignancies and Cardiovascular Diseases | BEN GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) | 2008-12-04 | — | — | US | disclosed |
| US-4332884-A | USING A DIOXIME CHELATING AGENT | RICOH CO., LTD. (JP) | 1982-06-01 | — | — | US | disclosed |
| US-4306014-A | AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM | RICOH CO., LTD. (JP) | 1981-12-15 | — | — | US | disclosed |
| US-4201588-A | NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, CARBAZIDES OR QUINONES AS PHOTOREDUCTANT; EXTERNAL HYDROGEN SOURCE | EASTMAN KODAK COMPANY (US) | 1980-05-06 | — | — | US | disclosed |
| US-4171221-A | NONSILVER PHOTOGTAPHY | EASTMAN KODAK COMPANY (US) | 1979-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180099917-A1 | REVERSIBLY REDUCIBLE MATERIALS AND USE THEREOF | NES, CBR3, SQOR | APAF1 4670/4885TDP2 4439/4885NSD2 124/4885 |
| US-20080300274-A1 | Novel Pyrrolidino-1,4-Naphthoquinone Deriviatives and their Use for Treating Malignancies and Cardiovascular Diseases | MAPK1, MAP3K1, MAP3K20 | APAF1 1872/4885TDP2 2053/4885NSD2 3596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.