Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11651881 | 0.98 | ATM (0.46) | ATMHTTGAACYP2C19DRD4 | |
| SCHEMBL27362330 | 0.89 | HPGD (0.52) | ATMHTTGAACYP2C19DRD4 | |
| SCHEMBL8899427 | 0.81 | ATM (0.45) | ATMHTTGAACYP2C19DRD4 | |
| SCHEMBL7458259 | 0.79 | CA12 (0.46) | HTTGAACA12CA2CA9 | |
| SCHEMBL6161952 | 0.78 | GSK3B (0.48) | ATMHTTGAACYP2C19DRD4 | |
| SCHEMBL3891431 | 0.78 | GSK3B (0.48) | ATMHTTGAACYP2C19DRD4 | |
| SCHEMBL14747468 | 0.78 | ATM (0.46) | ATMHTTGAACYP2C19DRD4 | |
| SCHEMBL5918192 | 0.78 | ALDH1A1 (0.40) | HTTGAACYP2C19CA12CA1 | |
| SCHEMBL22024926 | 0.78 | GSK3B (0.48) | ATMHTTGAACYP2C19DRD4 | |
| SCHEMBL6630645 | 0.78 | ATM (0.46) | ATMHTTGAACYP2C19DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106543095-B | A method of benzo isoxazole is prepared based on 2- hydroxy acetophenone oxime and its one pot of derivative | 江苏大学 | 2019-03-05 | — | — | CN | claimed |
| CN-106543095-A | It is a kind of based on one pot of method for preparing benzoisoxazole of 2 hydroxy acetophenone oximes and its derivant | 江苏大学 | 2017-03-29 | — | — | CN | claimed |
| CN-101151382-B | Modification of copper/iron selectivity in copper solvent extraction systems | CYTEC TECH CORP | 2011-02-02 | — | — | CN | claimed |
| CN-101151382-A | Modification of copper/iron selectivity in copper solvent extraction systems | CYTEC TECH CORP (US) | 2008-03-26 | — | — | CN | claimed |
| CN-100351405-C | Composition and process for solvent extraction of metals with aldoxime or ketoxime extractants | CYTEC TECH CORP (US) | 2007-11-28 | — | — | CN | claimed |
| CN-1774517-A | Composition and process for the solvent extraction of metals using aldoxime or ketoxime extractants | CYTEC TECH CORP (US) | 2006-05-17 | — | — | CN | claimed |
| US-20060074108-A1 | Matrix metalloprotease (MMP) inhibitors and their application in cosmetic and pharmaceutical composition | BIODERM RESEARCH (US) | 2006-04-06 | — | — | US | claimed |
| US-20050271608-A1 | Skin whitening compositions based on hydroxyaryl alkyl ketones and their isosteric derivatives | GUPTA SHYAM K | 2005-12-08 | — | — | US | claimed |
| US-6576335-B2 | Used to replace the costly and toxic solvent extraction steps of conventional copper processing; preferential; for recovering copper from aqueous solutions in the copper mining and copper plating industries | BECHTEL BWXT IDAHO, LLC | 2003-06-10 | — | — | US | claimed |
| US-20020114961-A1 | Solid-phase materials for chelating metal ions and methods of making and using same | BECHTEL BWTX IDAHO, LLC | 2002-08-22 | — | — | US | claimed |
| EP-0329416-A2 | Process for preparing 4-hydroxyacetophenone oxime with mother liquor recycle | HOECHST CELANESE CORPORATION (US) | 1989-08-23 | — | — | EP | claimed |
| US-4855499-A | Novel process to prevent formation of chlorinated by-products in APAP production | HOECHST CELANESE CORPORATION (US) | 1989-08-08 | — | — | US | claimed |
| CN-116496174-A | Refining method of p-hydroxyacetophenone ammoximation reaction product | 江苏新瀚新材料股份有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-114534926-A | Flotation method and application of biohydroxy aromatic ketoxime serving as collecting agent in froth flotation | 重庆康普化学工业股份有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-109772592-B | Application of 2-hydroxy aronoxime compound as collecting agent in oxide ore flotation and flotation method | 广东省科学院资源综合利用研究所 | 2021-03-23 | — | — | CN | disclosed |
| CN-109772592-A | 2- hydroxyl arone oxime compound as collecting agent in oxide ore flotation application and method for floating | 广东省资源综合利用研究所 | 2019-05-21 | — | — | CN | disclosed |
| US-4100203-A | Oxidative coupling of alkylphenols or 1-naphthols catalyzed by metal complexes of an oxime of a keto or aldehyde compound | ICI AMERICAS INC. (US) | 1978-07-11 | — | — | US | disclosed |
| US-4097462-A | OXIDATIVE COUPLING OF A PHENOL, PRECIPITATION, MANGANESE (II) HYDROXYOXIME CHELATE CATALYST | GENERAL ELECTRIC COMPANY (US) | 1978-06-27 | — | — | US | disclosed |
| US-4075174-A | BIS-SECONDARY DIAMINES | GENERAL ELECTRIC COMPANY (US) | 1978-02-21 | — | — | US | disclosed |
| US-3956242-A | Preparation of polyphenylene oxide using a manganese (II) ω-hydroxyoxime chelate reaction promoter | GENERAL ELECTRIC COMPANY (US) | 1976-05-11 | — | — | US | disclosed |