SCHEMBL24705449

SCHEMBL24705449

C=C(Cl)C(=O)OCCNC(=O)C(CC(C)C)N1C(=O)c2cc(Oc3ccc(Cl)cc3)c3c4c(Oc5ccc(Cl)cc5)cc5c6c(cc(Oc7ccc(Cl)cc7)c(c7c(Oc8ccc(Cl)cc8)cc(c2c37)C1=O)c64)C(=O)N(C(CC(C)C)C(=O)NCCOC(=O)C(=C)Cl)C5=O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.34
MEN1 O00255 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
KMT2A Q03164 1/20 0.34
ATM Q13315 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
ALDH1A1 P00352 2/20 0.34
GAA P10253 1/20 0.34
TP53 P04637 2/20 0.33
MAPT P10636 1/20 0.33
GCK P35557 1/20 0.33
MDM2 Q00987 1/20 0.32
USP2 O75604 1/20 0.32
TSHR P16473 1/20 0.32
HPGD P15428 1/20 0.32
MCL1 Q07820 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24705129 0.94 ALDH1A1 (0.33) SMN1; SMN2MEN1CYP1A2CYP3A4CYP2D6
SCHEMBL24704993 0.93 CARM1 (0.34) SMN1; SMN2MEN1CYP1A2CYP3A4CYP2D6
SCHEMBL24705454 0.91 MAPT (0.37) SMN1; SMN2MEN1CYP1A2CYP3A4CYP2D6
SCHEMBL24704982 0.91 ALDH1A1 (0.36) SMN1; SMN2MEN1CYP1A2CYP3A4CYP2D6
SCHEMBL24705406 0.91 LMNA (0.33) SMN1; SMN2MEN1KMT2AALDH1A1GAA
SCHEMBL24704983 0.91 SCN9A (0.34) SMN1; SMN2ALDH1A1GAATP53MAPT
SCHEMBL24705183 0.87 ALDH1A1 (0.34) SMN1; SMN2MEN1CYP1A2CYP3A4CYP2D6
SCHEMBL24705531 0.86 ALDH1A1 (0.37) SMN1; SMN2ALDH1A1GAATP53MAPT
SCHEMBL24704837 0.85 LMNA (0.33) SMN1; SMN2MEN1CYP1A2CYP3A4CYP2D6
SCHEMBL24705089 0.85 PPARG (0.38) SMN1; SMN2CYP1A2CYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220389014-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM MANUFACTURED THEREFROM, BACKLIGHT UNIT, AND DISPLAY DEVICE LG CHEM, LTD. (KR) 2022-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220389014-A1 COMPOUND, PHOTOSENSITIVE FLUORESCENT RESIN COMPOSITION COMPRISING SAME, COLOR CONVERSION FILM MANUFACTURED THEREFROM, BACKLIGHT UNIT, AND DISPLAY DEVICE NOTUM, THEM6, FAR1 SMN1; SMN2 3479/4885MEN1 2097/4885CYP1A2 1355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.