Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3605697 | 0.79 | PDE4D (0.55) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL28052513 | 0.71 | SMN1; SMN2 (0.46) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL2389958 | 0.71 | PDE4A (0.61) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL17003768 | 0.69 | PDE4D (0.50) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL24708041 | 0.67 | PDE4D (0.48) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL3606207 | 0.67 | PDE4D (0.42) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL12096338 | 0.67 | SMN1; SMN2 (0.54) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL12096274 | 0.67 | KDM1A (0.46) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL31662983 | 0.67 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL27999976 | 0.67 | NOS3 (0.50) | PDE4APDE4BPDE4CPDE4DPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253959-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR USE IN NEURODEGENERATIVE DISORDERS | UNIVERSITEIT HASSELT (BE) | 2022-12-08 | — | — | WO | disclosed |