Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 4/20 | 0.50 |
| ▸ | NOS1 | P29475 | 4/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 3/20 | 0.33 |
| ▸ | KMO | O15229 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1758759 | 0.75 | PNMT (0.36) | PRMT5WDR77KMOLMNAHPGD | |
| SCHEMBL28785941 | 0.72 | METAP2 (0.36) | — | |
| SCHEMBL12697235 | 0.71 | NOS3 (0.50) | NOS3NOS1CSNK2A1LMNAHPGD | |
| SCHEMBL13675220 | 0.70 | SRD5A2 (0.40) | NOS3NOS1PDE4APDE4BPDE4C | |
| SCHEMBL20472358 | 0.69 | CSNK2A1 (0.47) | NOS3NOS1CSNK2A1 | |
| SCHEMBL6490259 | 0.69 | CSNK2A1 (0.56) | NOS3NOS1CSNK2A1LMNACYP1A2 | |
| SCHEMBL12695021 | 0.69 | CSNK2A1 (0.47) | NOS3NOS1CSNK2A1LMNATSHR | |
| SCHEMBL2389958 | 0.67 | PDE4A (0.61) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL28139354 | 0.67 | CSNK2A1 (0.45) | NOS3NOS1CSNK2A1PDE4APDE4B | |
| SCHEMBL3605697 | 0.67 | PDE4D (0.55) | PDE4APDE4BPDE4CPDE4DPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104507922-A | Novel method for producing optically pure and optionally substituted 2- (1-hydroxy-alkyl) -chromen-4-one derivatives and the use thereof for producing medicaments | RHIZEN PHARMACEUTICALS SA | 2015-04-08 | — | — | CN | disclosed |