Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.52 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.45 |
| ▸ | CYP27B1 | O15528 | 2/20 | 0.44 |
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2465539 | 0.88 | NPC1 (0.50) | SLC6A9SLC6A5RAB9ASMN1; SMN2GAA | |
| SCHEMBL2470778 | 0.84 | GPR139 (0.53) | GPR139SLC6A9SLC6A5RAB9ASMN1; SMN2 | |
| SCHEMBL2467017 | 0.81 | GPR139 (0.55) | GPR139SLC6A9SLC6A5RAB9ASMN1; SMN2 | |
| SCHEMBL2466996 | 0.80 | GPR139 (0.51) | GPR139SLC6A9SLC6A5RAB9ASMN1; SMN2 | |
| SCHEMBL2462152 | 0.79 | GPR139 (0.52) | GPR139SLC6A9SLC6A5RAB9ASMN1; SMN2 | |
| SCHEMBL5262774 | 0.78 | SLC6A9 (0.54) | GPR139SLC6A9SLC6A5RAB9ASMN1; SMN2 | |
| SCHEMBL2468306 | 0.78 | GPR139 (0.51) | GPR139SLC6A9SLC6A5RAB9ASMN1; SMN2 | |
| SCHEMBL14243641 | 0.78 | SLC6A9 (0.51) | GPR139SLC6A9SLC6A5RAB9ASMN1; SMN2 | |
| SCHEMBL2466993 | 0.77 | GPR139 (0.50) | GPR139SLC6A9SLC6A5RAB9ASMN1; SMN2 | |
| SCHEMBL2470759 | 0.77 | GPR139 (0.50) | GPR139SLC6A9SLC6A5RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2539378-A1 | HALOGENATED AMIDE ESTER AND INTERNAL ELECTRON DONOR WITH SAME | Dow Global Technologies LLC (US) | 2013-01-02 | — | — | EP | disclosed |
| WO-2011106497-A1 | HALOGENATED AMIDE ESTER AND INTERNAL ELECTRON DONOR WITH SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-09-01 | — | — | WO | disclosed |