Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | P2RY10 | O00398 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5270751 | 0.94 | POLB (0.47) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL105672 | 0.91 | ALDH1A1 (0.49) | POLBAPEX1HTTTDP1TSHR | |
| Phosphoric Acid SCHEMBL17764817 | 0.90 | ALDH1A1 (0.48) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL28104073 | 0.85 | POLB (0.43) | POLBAPEX1HTTTDP1ALDH1A1 | |
| SCHEMBL17488930 | 0.85 | ALDH1A1 (0.43) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL6234773 | 0.85 | POLB (0.46) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL3691946 | 0.84 | POLB (0.48) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL17488997 | 0.83 | SRC (0.53) | POLBTDP1TSHRALDH1A1SRC | |
| SCHEMBL28575474 | 0.83 | ALDH1A1 (0.43) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL7052527 | 0.82 | POLB (0.50) | POLBAPEX1HTTTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374444-B1 | Dental covering material | VOCO GMBH (DE) | 2017-03-01 | — | — | EP | claimed |
| EP-2374444-A2 | Dental covering material | VOCO GmbH (DE) | 2011-10-12 | — | — | EP | claimed |
| EP-3011949-B1 | CURABLE DENTAL MATERIAL | VOCO GMBH (DE) | 2021-05-05 | — | — | EP | disclosed |
| EP-2436364-B1 | Varnish compound comprising a monomer with a polyalicyclic structure element | VOCO GMBH (DE) | 2017-05-31 | — | — | EP | disclosed |
| EP-2436365-B1 | Composite material comprising a monomer with a polyalicyclic structure element | VOCO GMBH (DE) | 2017-03-08 | — | — | EP | disclosed |
| EP-2374444-B1 | Dental covering material | VOCO GMBH (DE) | 2017-03-01 | — | — | EP | disclosed |
| EP-3011949-A1 | CURABLE DENTAL MATERIAL | VOCO GmbH (DE) | 2016-04-27 | — | — | EP | disclosed |
| EP-2374445-B1 | Dual hardening multi-component dental composition | VOCO GMBH (DE) | 2015-07-29 | — | — | EP | disclosed |
| EP-2436366-B1 | Composite material comprising a monomer with a polyalicyclic structure as sealing material | VOCO GMBH (DE) | 2015-07-29 | — | — | EP | disclosed |
| EP-2374444-A2 | Dental covering material | VOCO GmbH (DE) | 2011-10-12 | — | — | EP | disclosed |
| EP-2374445-A2 | Dual hardening multi-component dental composition | VOCO GmbH (DE) | 2011-10-12 | — | — | EP | disclosed |