Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL345074 | 0.92 | POLB (0.42) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL7052527 | 0.88 | POLB (0.50) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL2470935 | 0.85 | POLB (0.52) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL15412 | 0.80 | TSHR (0.55) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL105672 | 0.80 | ALDH1A1 (0.49) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL5270751 | 0.80 | POLB (0.47) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL28104073 | 0.80 | POLB (0.43) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL20283752 | 0.79 | TDP1 (0.43) | POLBAPEX1HTTTDP1MAPT | |
| Phosphoric Acid SCHEMBL17764817 | 0.79 | ALDH1A1 (0.48) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL28245779 | 0.79 | TSHR (0.53) | POLBAPEX1HTTTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1269968-B1 | Dental cement composition | KURARAY CO (JP) | 2005-10-12 | — | — | EP | disclosed |
| EP-1269967-B1 | Dental composition kit | KURARAY CO (JP) | 2005-05-18 | — | — | EP | disclosed |
| US-6869984-B2 | Dental composition kit | KURARAY CO., LTD. (JP) | 2005-03-22 | — | — | US | disclosed |
| US-20030083398-A1 | Dental composition kit | KURARAY CO. LTD. (JP) | 2003-05-01 | — | — | US | disclosed |
| EP-1269967-A1 | Dental composition kit | KURARAY CO., LTD. (JP) | 2003-01-02 | — | — | EP | disclosed |
| EP-1269968-A1 | Dental cement composition | KURARAY CO., LTD. (JP) | 2003-01-02 | — | — | EP | disclosed |