Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6234773 | 0.88 | POLB (0.46) | POLBTDP1APEX1HTTTSHR | |
| SCHEMBL2470935 | 0.82 | POLB (0.52) | POLBTDP1APEX1HTTTSHR | |
| SCHEMBL10728057 | 0.82 | POLB (0.60) | POLBTDP1APEX1HTTTSHR | |
| SCHEMBL345074 | 0.80 | POLB (0.42) | POLBTDP1APEX1HTTTSHR | |
| SCHEMBL10734333 | 0.79 | HTT (0.64) | POLBTDP1APEX1HTTTSHR | |
| SCHEMBL28066767 | 0.79 | TSHR (0.62) | POLBTDP1APEX1HTTTSHR | |
| SCHEMBL15412 | 0.78 | TSHR (0.55) | POLBTDP1APEX1HTTTSHR | |
| SCHEMBL105672 | 0.78 | ALDH1A1 (0.49) | POLBTDP1APEX1HTTTSHR | |
| SCHEMBL7052523 | 0.78 | NPSR1 (0.39) | TDP1ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL5270751 | 0.78 | POLB (0.47) | POLBTDP1APEX1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030055123-A1 | Dental cement composition | KURARAY CO. LTD, (JP) | 2003-03-20 | — | — | US | disclosed |