Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9371623 | 0.74 | EPHX2 (0.43) | ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL7374226 | 0.72 | HCAR2 (0.35) | KDM4EALDH1A1GAASMN1; SMN2HCAR2 | |
| SCHEMBL127895 | 0.72 | HCAR2 (0.35) | KDM4EALDH1A1GAASMN1; SMN2HCAR2 | |
| SCHEMBL11393869 | 0.69 | FDPS (0.46) | KDM4EALDH1A1SMN1; SMN2HCAR2 | |
| SCHEMBL12631200 | 0.68 | ALDH1A1 (0.41) | KDM4EALDH1A1GAASMN1; SMN2HCAR2 | |
| SCHEMBL19224495 | 0.67 | LMNA (0.56) | KDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL741431 | 0.67 | ALDH1A1 (0.40) | KDM4EALDH1A1GAASMN1; SMN2HCAR2 | |
| SCHEMBL21199834 | 0.66 | CCNE1 (0.52) | KDM4EALDH1A1SMN1; SMN2HCAR2 | |
| SCHEMBL27556089 | 0.65 | — | — | |
| SCHEMBL24533146 | 0.64 | SMN1; SMN2 (0.55) | ALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106627-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-09-01 | — | — | WO | disclosed |