Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.35 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.32 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30122098 | 1.00 | RORC (0.36) | RORCKLKB1ALDH1A1KDM4ESLC16A3 | |
| SCHEMBL24709688 | 0.71 | RORC (0.42) | RORCKLKB1ALDH1A1POLBTSHR | |
| SCHEMBL30122262 | 0.71 | RORC (0.35) | RORCKLKB1ALDH1A1SLC16A3SLC16A1 | |
| SCHEMBL31076499 | 0.67 | ALDH1A1 (0.40) | ALDH1A1KDM4ETP53MEN1KMT2A | |
| SCHEMBL20477408 | 0.67 | ALDH1A1 (0.40) | ALDH1A1KDM4EPOLBTSHRMAPT | |
| SCHEMBL20477410 | 0.67 | ALDH1A1 (0.40) | ALDH1A1KDM4EPOLBTSHRMAPT | |
| SCHEMBL28529843 | 0.66 | ALDH1A1 (0.41) | ALDH1A1KDM4EPOLBTSHRMAPT | |
| SCHEMBL28529845 | 0.66 | ALDH1A1 (0.41) | ALDH1A1KDM4EPOLBTSHRMAPT | |
| SCHEMBL20477337 | 0.65 | CA5A (0.39) | KLKB1ALDH1A1KDM4EPOLBTSHR | |
| SCHEMBL20477336 | 0.65 | CA5A (0.39) | KLKB1ALDH1A1KDM4EPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022258052-A1 | HETEROCYCLIC LACTAM COMPOUND, AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | 劲方医药科技(上海)有限公司 | 2022-12-15 | — | — | WO | disclosed |