Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24522232 | 0.87 | L3MBTL1 (0.45) | L3MBTL1MAPK1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL13626620 | 0.81 | TAS1R3 (0.41) | TAS1R3TAS1R1KMT2AMEN1GAA | |
| SCHEMBL12674141 | 0.80 | TAS1R3 (0.41) | MAPK1POLBTAS1R3TAS1R1GAA | |
| SCHEMBL24710213 | 0.79 | L3MBTL1 (0.59) | L3MBTL1MAPK1PSIP1POLBKMT2A | |
| SCHEMBL12666642 | 0.78 | POLB (0.38) | MAPK1POLBTAS1R3TAS1R1KMT2A | |
| SCHEMBL25854719 | 0.77 | L3MBTL1 (0.49) | L3MBTL1MAPK1PSIP1POLBKMT2A | |
| SCHEMBL632881 | 0.75 | MAPT (0.47) | L3MBTL1MAPK1CYP3A4TAS1R3TAS1R1 | |
| SCHEMBL7132787 | 0.68 | L3MBTL1 (0.48) | L3MBTL1MAPK1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL632301 | 0.68 | L3MBTL1 (0.49) | L3MBTL1MAPK1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28907686 | 0.67 | L3MBTL1 (0.54) | L3MBTL1MAPK1PSIP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022261473-A1 | PROTEASE INHIBITORS FOR THE TREATMENT OF CORONAVIRUS INFECTIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-12-15 | — | — | WO | disclosed |