SCHEMBL247100

SCHEMBL247100

CC(C)(c1ccccc1)c1cccc(OC(=O)O)c1C(C)(C)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.40
ATM Q13315 1/20 0.40
ALDH1A1 P00352 6/20 0.37
ESR1 P03372 1/20 0.37
CYP3A4 P08684 1/20 0.37
ESR2 Q92731 1/20 0.37
MAPT P10636 2/20 0.36
KMT2A Q03164 2/20 0.36
KDM4E B2RXH2 5/20 0.36
HSD17B10 Q99714 1/20 0.36
KCNN4 O15554 1/20 0.35
CYP2C19 P33261 1/20 0.35
HIF1A Q16665 1/20 0.35
ELANE P08246 2/20 0.35
GAA P10253 1/20 0.35
RXRA P19793 1/20 0.35
RXRB P28702 1/20 0.35
RXRG P48443 1/20 0.35
ALOX15 P16050 1/20 0.34
HDAC3 O15379 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29601094 1.00 TDP1 (0.40) TDP1ATMALDH1A1ESR1CYP3A4
SCHEMBL247099 0.91 TDP1 (0.40) TDP1ATMALDH1A1ESR1CYP3A4
SCHEMBL1157238 0.88 TDP1 (0.37) TDP1ATMALDH1A1ESR1CYP3A4
SCHEMBL1673996 0.87 TDP1 (0.47) TDP1ATMALDH1A1ESR1CYP3A4
SCHEMBL245087 0.85 ATM (0.37) TDP1ATMALDH1A1ESR1CYP3A4
SCHEMBL27488778 0.85 TDP1 (0.37) TDP1ATMALDH1A1ESR1CYP3A4
SCHEMBL27819527 0.85 ATM (0.37) TDP1ATMALDH1A1ESR1CYP3A4
SCHEMBL1870707 0.85 ATM (0.37) TDP1ATMALDH1A1ESR1CYP3A4
SCHEMBL7647735 0.84 CHRM2 (0.39) ALDH1A1ESR1CYP3A4ESR2MAPT
SCHEMBL1681408 0.84 KDM4E (0.45) TDP1ATMALDH1A1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6734278-B2 MELT ESTER INTERCHANGE BAYER AKTIENGESELLSCHAFT (DE) 2004-05-11 US claimed
US-20030139564-A1 Production of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-07-24 US claimed
US-5322919-A Transesterification in an inert solvent IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1994-06-21 US claimed
US-5151491-A Nitrogen compound, a boric acid compound and a dihydroxy compound terminated with a monoalcohol GE PLASTICS JAPAN, LTD. (JP) 1992-09-29 US claimed
EP-3174935-B1 COPOLYCARBONATE COMPOUNDS WITH CYCLIC AND LINEAR OLIGOMERS AND IMPROVED OPTICAL PROPERTIES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-06-21 EP disclosed
EP-3174934-B1 COPOLYCARBONATE COMPOUNDS WITH CYCLIC AND LINEAR OLIGOMERS AND IMPROVED RHEOLOGICAL PROPERTIES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-06-14 EP disclosed
EP-3227374-B1 COPOLYCARBONATE COMPOUNDS WITH IMPROVED RHEOLOGICAL AND OPTICAL PROPERTIES CONTAINING DIGLYCEROLESTER COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2022-06-01 EP disclosed
CN-107207845-B Copolycarbonate compositions comprising PE-waxes with improved processability 科思创德国股份有限公司 2021-03-12 CN disclosed
CN-107207846-B Copolycarbonate compositions comprising diglyceride with improved rheological and optical properties 科思创德国股份有限公司 2020-05-19 CN disclosed
US-10272654-B2 Polycarbonate composition having improved flame resistance for extrusion applications COVESTRO DEUTSCHLAND AG (DE) 2019-04-30 US disclosed
EP-2679575-B1 PROCESS FOR PRODUCING CARBONYL COMPOUNDS ASAHI CHEMICAL IND (JP) 2019-04-10 EP disclosed
EP-3452530-A1 COPOLYCARBONATE AS A SUPPORTING MATERIAL IN 3-D PRINTING Covestro Deutschland AG (DE) 2019-03-13 EP disclosed
US-5322919-A Transesterification in an inert solvent IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1994-06-21 US disclosed
US-5276129-A Aromatic polycarbonates with excellent color tone, heat resistance and water resistance GE PLASTICS JAPAN, LTD. (JP) 1994-01-04 US disclosed
EP-0561363-A2 Process for producing polycarbonate IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1993-09-22 EP disclosed
US-5187242-A Workable molding materials containing aliphatic carboxylic acids and aromatic diols as monomers, impact strenth, transparency GENERAL ELECTRIC COMPANY (US) 1993-02-16 US disclosed
US-5151491-A Nitrogen compound, a boric acid compound and a dihydroxy compound terminated with a monoalcohol GE PLASTICS JAPAN, LTD. (JP) 1992-09-29 US disclosed
EP-0488182-A2 Process for producing a polycarbonate IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1992-06-03 EP disclosed
EP-0434998-A2 Polycarbonate or polyestercarbonate resin compositions and preparing methods thereof GE PLASTICS JAPAN LIMITED (JP) 1991-07-03 EP disclosed
EP-0360578-A2 Process for the production of polycarbonates GE PLASTICS JAPAN LTD. (JP) 1990-03-28 EP disclosed