SCHEMBL27488778

SCHEMBL27488778

CC(C)(c1ccccc1)c1cccc(OC(=O)CO)c1C(C)(C)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.37
ATM Q13315 1/20 0.37
CYP2C19 P33261 1/20 0.35
HIF1A Q16665 1/20 0.35
KIF11 P52732 1/20 0.35
KDM4E B2RXH2 9/20 0.35
ALDH1A1 P00352 6/20 0.35
GAA P10253 2/20 0.35
PPARG P37231 2/20 0.35
RXRA P19793 1/20 0.35
RXRB P28702 1/20 0.35
RXRG P48443 1/20 0.35
MEN1 O00255 4/20 0.34
KMT2A Q03164 4/20 0.34
POLB P06746 2/20 0.34
RECQL P46063 1/20 0.34
LMNA P02545 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
HTT P42858 2/20 0.33
ESR1 P03372 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1681408 0.88 KDM4E (0.45) TDP1ATMCYP2C19HIF1AKDM4E
SCHEMBL247099 0.85 TDP1 (0.40) TDP1ATMCYP2C19HIF1AKDM4E
SCHEMBL29601094 0.85 TDP1 (0.40) TDP1ATMCYP2C19HIF1AKDM4E
SCHEMBL247100 0.85 TDP1 (0.40) TDP1ATMCYP2C19HIF1AKDM4E
SCHEMBL1681409 0.84 MEN1 (0.42) TDP1ATMCYP2C19HIF1AKDM4E
SCHEMBL6566813 0.81 KIF11 (0.43) KIF11
SCHEMBL1870707 0.81 ATM (0.37) TDP1ATMCYP2C19HIF1AKDM4E
SCHEMBL27819527 0.81 ATM (0.37) TDP1ATMCYP2C19HIF1AKDM4E
SCHEMBL245087 0.81 ATM (0.37) TDP1ATMCYP2C19KDM4EALDH1A1
SCHEMBL10631084 0.80 SMN1; SMN2 (0.32) TDP1ATMKDM4EALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113260670-B Polystyrene resin composition 出光兴产株式会社 2024-10-29 CN claimed
CN-1319860-C Magnesium hydroxide particles, flame retardant resin composition and formed products thereof KYOWA CHEM IND CO LTD (JP) 2007-06-06 CN disclosed
CN-1572726-A Magnesium hydroxide particles, flame retardant resin composition and formed products thereof KYOWA CHEM IND CO LTD (JP) 2005-02-02 CN disclosed
CN-1177760-C Method for producing magnesium hydroxide particles Э�ͻ�ѧ��ҵ��ʽ���� 2004-12-01 CN disclosed
CN-1297423-A Magnesium hydroxide particles, process for producing the same, and particle-containing resin composition KYOWA CHEM IND CO LTD (JP) 2001-05-30 CN disclosed